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    OR51B4 olfactory receptor family 51 subfamily B member 4 [ Homo sapiens (human) ]

    Gene ID: 79339, updated on 9-Dec-2024

    Summary

    Official Symbol
    OR51B4provided by HGNC
    Official Full Name
    olfactory receptor family 51 subfamily B member 4provided by HGNC
    Primary source
    HGNC:HGNC:14708
    See related
    Ensembl:ENSG00000183251 AllianceGenome:HGNC:14708
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    HOR5'Beta1
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
    Orthologs
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    Genomic context

    See OR51B4 in Genome Data Viewer
    Location:
    11p15.4
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (5301014..5301946, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (5360366..5361298, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (5322244..5323176, complement)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene beta-globin locus control region Neighboring gene hemoglobin subunit epsilon 1 Neighboring gene olfactory receptor family 51 subfamily AB member 1 pseudogene Neighboring gene olfactory receptor family 51 subfamily B member 3 pseudogene Neighboring gene olfactory receptor family 51 subfamily B member 2

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables olfactory receptor activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in membrane NAS
    Non-traceable Author Statement
    more info
    PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    olfactory receptor 51B4
    Names
    odorant receptor HOR5'beta1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_033179.2NP_149419.2  olfactory receptor 51B4

      See identical proteins and their annotated locations for NP_149419.2

      Status: VALIDATED

      Source sequence(s)
      BC153815
      Consensus CDS
      CCDS7757.1
      UniProtKB/Swiss-Prot
      A7MAV5, Q6NTD7, Q9Y5P0
      UniProtKB/TrEMBL
      A4FU14
      Related
      ENSP00000369573.1, ENST00000380224.2
      Conserved Domains (2) summary
      pfam00001
      Location:39289
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:29305
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      Range
      5301014..5301946 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060935.1 Alternate T2T-CHM13v2.0

      Range
      5360366..5361298 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)