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    Ltn1 listerin E3 ubiquitin protein ligase 1 [ Mus musculus (house mouse) ]

    Gene ID: 78913, updated on 23-Jun-2021

    Summary

    Official Symbol
    Ltn1provided by MGI
    Official Full Name
    listerin E3 ubiquitin protein ligase 1provided by MGI
    Primary source
    MGI:MGI:1926163
    See related
    Ensembl:ENSMUSG00000052299
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Li; Rnf1; Zfp29; C87237; Rnf160; Zfp294; AV266914; Listerin; 4930528H02Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 9.3), CNS E18 (RPKM 6.0) and 26 other tissues See more
    Orthologs
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    Genomic context

    See Ltn1 in Genome Data Viewer
    Location:
    16; 16 C3.3
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (87173539..87229504, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (87376651..87432619, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (87376896..87432851, complement)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 41484 Neighboring gene N-6 adenine-specific DNA methyltransferase 1 (putative) Neighboring gene predicted gene, 25896 Neighboring gene RWD domain containing 2B Neighboring gene ubiquitin specific peptidase 16 Neighboring gene chaperonin containing Tcp1, subunit 8 (theta)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • KIAA0714

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ribosomal large subunit binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables ubiquitin protein ligase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables ubiquitin-protein transferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in protein autoubiquitination IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in rescue of stalled ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in ribosome-associated ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of RQC complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    E3 ubiquitin-protein ligase listerin
    Names
    RING-type E3 ubiquitin transferase listerin
    ring finger protein 160
    zfp-294
    zinc finger protein 294
    NP_001074537.1
    XP_036016076.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081068.1NP_001074537.1  E3 ubiquitin-protein ligase listerin

      See identical proteins and their annotated locations for NP_001074537.1

      Status: PROVISIONAL

      Source sequence(s)
      AC140319
      Consensus CDS
      CCDS37382.1
      UniProtKB/Swiss-Prot
      Q6A009
      Related
      ENSMUSP00000038775.8, ENSMUST00000039449.9
      Conserved Domains (1) summary
      pfam13639
      Location:17141763
      zf-RING_2; Ring finger domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      87173539..87229504 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036160183.1XP_036016076.1  E3 ubiquitin-protein ligase listerin isoform X1

      Conserved Domains (1) summary
      COG5219
      Location:640928
      COG5219; Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]

    RNA

    1. XR_384950.5 RNA Sequence

    2. XR_384951.5 RNA Sequence

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