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    Scyl1 SCY1-like 1 (S. cerevisiae) [ Mus musculus (house mouse) ]

    Gene ID: 78891, updated on 23-Jun-2021

    Summary

    Official Symbol
    Scyl1provided by MGI
    Official Full Name
    SCY1-like 1 (S. cerevisiae)provided by MGI
    Primary source
    MGI:MGI:1931787
    See related
    Ensembl:ENSMUSG00000024941
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Nt; mdf; mfd; p10; Ntkl; p105; C85140; 2810011O19Rik
    Expression
    Ubiquitous expression in ovary adult (RPKM 46.3), genital fat pad adult (RPKM 42.0) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Scyl1 in Genome Data Viewer
    Location:
    19 A; 19 4.34 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (5808450..5821461, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (5758422..5771419, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (5758427..5771401, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 89, member B Neighboring gene zinc ribbon domain containing 2 Neighboring gene latent transforming growth factor beta binding protein 3 Neighboring gene Malat1-associated small cytoplasmic RNA Neighboring gene metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) Neighboring gene nuclear paraspeckle assembly transcript 1 (non-protein coding)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    Associated conditions

    Description Tests
    muscle deficient
    GeneReviews: Not available

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Spontaneous (1) 
    • Targeted (2)  1 citation
    • Chemically induced (ENU) (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of COPI vesicle coat IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of COPI vesicle coat ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cis-Golgi network ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum-Golgi intermediate compartment ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    N-terminal kinase-like protein
    Names
    105 kDa kinase-like protein
    SCY1-like protein 1
    mitosis-associated kinase-like protein NTKL
    ubiquitous protein kinase-like (105 kDa)

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001361921.1NP_001348850.1  N-terminal kinase-like protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC134563, AK145869, HM856325
      Consensus CDS
      CCDS89318.1
      Related
      ENSMUSP00000025890.10, ENSMUST00000025890.10
      Conserved Domains (3) summary
      PHA03169
      Location:591745
      PHA03169; hypothetical protein; Provisional
      cd14011
      Location:29296
      PK_SCY1_like; Pseudokinase domain of Scy1-like proteins
      sd00044
      Location:351372
      HEAT; HEAT repeat [structural motif]
    2. NM_001361922.1NP_001348851.1  N-terminal kinase-like protein isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC134563, AK134356, AK145869, HM856326
      Related
      ENSMUSP00000158420.2, ENSMUST00000236773.2
      Conserved Domains (2) summary
      cd14011
      Location:29296
      PK_SCY1_like; Pseudokinase domain of Scy1-like proteins
      sd00044
      Location:351372
      HEAT; HEAT repeat [structural motif]
    3. NM_023912.3NP_076401.1  N-terminal kinase-like protein isoform 1

      See identical proteins and their annotated locations for NP_076401.1

      Status: VALIDATED

      Source sequence(s)
      AC134563
      Consensus CDS
      CCDS29480.1
      UniProtKB/Swiss-Prot
      Q9EQC5
      Related
      ENSMUSP00000157476.2, ENSMUST00000236978.2
      Conserved Domains (2) summary
      cd14011
      Location:29296
      PK_SCY1_like; Pseudokinase domain of Scy1-like proteins
      sd00044
      Location:351372
      HEAT; HEAT repeat [structural motif]

    RNA

    1. NR_155264.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC134563, AK145869, HM856326
      Related
      ENSMUST00000235599.2

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      5808450..5821461 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030251145.2XP_030107005.1  N-terminal kinase-like protein isoform X1

      Conserved Domains (2) summary
      cd14011
      Location:29296
      PK_SCY1_like; Pseudokinase domain of Scy1-like proteins
      sd00044
      Location:351372
      HEAT; HEAT repeat [structural motif]

    RNA

    1. XR_388273.4 RNA Sequence

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