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    Scyl1 SCY1-like 1 (S. cerevisiae) [ Mus musculus (house mouse) ]

    Gene ID: 78891, updated on 28-Aug-2018

    Summary

    Official Symbol
    Scyl1provided by MGI
    Official Full Name
    SCY1-like 1 (S. cerevisiae)provided by MGI
    Primary source
    MGI:MGI:1931787
    See related
    Ensembl:ENSMUSG00000024941
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mdf; mfd; Ntkl; p105; C85140; 2810011O19Rik
    Expression
    Ubiquitous expression in ovary adult (RPKM 46.3), genital fat pad adult (RPKM 42.0) and 28 other tissues See more
    Orthologs

    Genomic context

    See Scyl1 in Genome Data Viewer
    Location:
    19 A; 19 4.34 cM
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 19 NC_000085.6 (5758422..5771414, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (5758427..5771401, complement)

    Chromosome 19 - NC_000085.6Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 89, member B Neighboring gene Sjogren syndrome/scleroderma autoantigen 1 Neighboring gene latent transforming growth factor beta binding protein 3 Neighboring gene metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) Neighboring gene nuclear paraspeckle assembly transcript 1 (non-protein coding)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Phenotypes

    Associated conditions

    Description Tests
    muscle deficient
    GeneReviews: Not available

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    retrograde vesicle-mediated transport, Golgi to ER ISO
    Inferred from Sequence Orthology
    more info
     
    vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    COPI vesicle coat IDA
    Inferred from Direct Assay
    more info
    PubMed 
    COPI vesicle coat ISO
    Inferred from Sequence Orthology
    more info
     
    Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    cis-Golgi network ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    endoplasmic reticulum-Golgi intermediate compartment ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    N-terminal kinase-like protein
    Names
    105 kDa kinase-like protein
    SCY1-like protein 1
    mitosis-associated kinase-like protein NTKL
    ubiquitous protein kinase-like (105 kDa)

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001361921.1NP_001348850.1  N-terminal kinase-like protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC134563, AK145869, HM856325
      Conserved Domains (3) summary
      PHA03169
      Location:591745
      PHA03169; hypothetical protein; Provisional
      cd14011
      Location:29296
      PK_SCY1_like; Pseudokinase domain of Scy1-like proteins
      sd00044
      Location:351372
      HEAT; HEAT repeat [structural motif]
    2. NM_001361922.1NP_001348851.1  N-terminal kinase-like protein isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC134563, AK134356, AK145869, HM856326
      Conserved Domains (2) summary
      cd14011
      Location:29296
      PK_SCY1_like; Pseudokinase domain of Scy1-like proteins
      sd00044
      Location:351372
      HEAT; HEAT repeat [structural motif]
    3. NM_023912.3NP_076401.1  N-terminal kinase-like protein isoform 1

      See identical proteins and their annotated locations for NP_076401.1

      Status: VALIDATED

      Source sequence(s)
      AC134563
      Consensus CDS
      CCDS29480.1
      UniProtKB/Swiss-Prot
      Q9EQC5
      Related
      ENSMUSP00000025890.8, ENSMUST00000025890.8
      Conserved Domains (2) summary
      cd14011
      Location:29296
      PK_SCY1_like; Pseudokinase domain of Scy1-like proteins
      sd00044
      Location:351372
      HEAT; HEAT repeat [structural motif]

    RNA

    1. NR_155264.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC134563, AK145869, HM856326

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000085.6 Reference GRCm38.p4 C57BL/6J

      Range
      5758422..5771414 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006531857.2XP_006531920.1  N-terminal kinase-like protein isoform X2

      UniProtKB/TrEMBL
      R4H4Y7
      Conserved Domains (3) summary
      PHA03169
      Location:591745
      PHA03169; hypothetical protein; Provisional
      cd14011
      Location:29296
      PK_SCY1_like; Pseudokinase domain of Scy1-like proteins
      sd00044
      Location:351372
      HEAT; HEAT repeat [structural motif]
    2. XM_006531856.2XP_006531919.1  N-terminal kinase-like protein isoform X1

      Conserved Domains (2) summary
      cd14011
      Location:29296
      PK_SCY1_like; Pseudokinase domain of Scy1-like proteins
      sd00044
      Location:351372
      HEAT; HEAT repeat [structural motif]

    RNA

    1. XR_388273.2 RNA Sequence

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