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    Ncapd3 non-SMC condensin II complex, subunit D3 [ Mus musculus (house mouse) ]

    Gene ID: 78658, updated on 23-Jun-2021

    Summary

    Official Symbol
    Ncapd3provided by MGI
    Official Full Name
    non-SMC condensin II complex, subunit D3provided by MGI
    Primary source
    MGI:MGI:2142989
    See related
    Ensembl:ENSMUSG00000035024
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI195468; AU018739; mKIAA0056; 2810487N22Rik; 4632407J06Rik; B130055D15Rik
    Expression
    Ubiquitous expression in liver E14.5 (RPKM 11.5), liver E14 (RPKM 11.1) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Ncapd3 in Genome Data Viewer
    Location:
    9; 9 A4
    Exon count:
    38
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (26941455..27008667)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (27030165..27096522)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (26837760..26902900)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene acyl-Coenzyme A dehydrogenase family, member 8 Neighboring gene thymocyte nuclear protein 1 Neighboring gene VPS26 retromer complex component B Neighboring gene junction adhesion molecule 3 Neighboring gene uncharacterized LOC115487155 Neighboring gene predicted gene, 53501

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables methylated histone binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within chromosome condensation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in meiotic chromosome condensation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within meiotic chromosome separation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in mitotic chromosome condensation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in mitotic chromosome condensation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in condensed chromosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in condensed chromosome, centromeric region IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of condensin complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of condensin complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of condensin complex TAS
    Traceable Author Statement
    more info
    PubMed 
    located_in germinal vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in kinetochore IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in pericentric heterochromatin ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    condensin-2 complex subunit D3
    Names
    Jacobsen syndrome region 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001382847.1NP_001369776.1  condensin-2 complex subunit D3 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC156163, CT025660
      Conserved Domains (2) summary
      sd00044
      Location:94123
      HEAT; HEAT repeat [structural motif]
      pfam12717
      Location:109285
      Cnd1; non-SMC mitotic condensation complex subunit 1
    2. NM_178113.4NP_835214.2  condensin-2 complex subunit D3 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC156163, CT025660
      Consensus CDS
      CCDS57665.1
      UniProtKB/Swiss-Prot
      Q6ZQK0
      UniProtKB/TrEMBL
      K4DI67, Q3UTU7, Q80W41
      Related
      ENSMUSP00000072871.8, ENSMUST00000073127.14
      Conserved Domains (3) summary
      sd00044
      Location:538566
      HEAT; HEAT repeat [structural motif]
      pfam12717
      Location:9511115
      Cnd1; non-SMC mitotic condensation complex subunit 1
      cl02544
      Location:538603
      VHS_ENTH_ANTH; VHS, ENTH and ANTH domain superfamily

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      26941455..27008667
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006510698.5XP_006510761.1  condensin-2 complex subunit D3 isoform X3

      Conserved Domains (3) summary
      sd00044
      Location:401429
      HEAT; HEAT repeat [structural motif]
      pfam12717
      Location:814978
      Cnd1; non-SMC mitotic condensation complex subunit 1
      cl02544
      Location:401466
      VHS_ENTH_ANTH; VHS, ENTH and ANTH domain superfamily
    2. XM_036155410.1XP_036011303.1  condensin-2 complex subunit D3 isoform X4

      Conserved Domains (2) summary
      sd00044
      Location:401429
      HEAT; HEAT repeat [structural motif]
      cl02544
      Location:401466
      VHS_ENTH_ANTH; VHS, ENTH and ANTH domain superfamily
    3. XM_006510697.5XP_006510760.1  condensin-2 complex subunit D3 isoform X2

      Conserved Domains (3) summary
      sd00044
      Location:538566
      HEAT; HEAT repeat [structural motif]
      pfam12717
      Location:9131058
      Cnd1; non-SMC mitotic condensation complex subunit 1
      cl02544
      Location:538603
      VHS_ENTH_ANTH; VHS, ENTH and ANTH domain superfamily
    4. XM_017313698.1XP_017169187.1  condensin-2 complex subunit D3 isoform X1

      UniProtKB/TrEMBL
      K4DI67
      Related
      ENSMUSP00000150938.2, ENSMUST00000216677.2
      Conserved Domains (3) summary
      sd00044
      Location:538566
      HEAT; HEAT repeat [structural motif]
      pfam12717
      Location:9511115
      Cnd1; non-SMC mitotic condensation complex subunit 1
      cl02544
      Location:538603
      VHS_ENTH_ANTH; VHS, ENTH and ANTH domain superfamily
    5. XM_011242627.4XP_011240929.1  condensin-2 complex subunit D3 isoform X5

      Conserved Domains (2) summary
      sd00044
      Location:222251
      HEAT; HEAT repeat [structural motif]
      pfam12717
      Location:237401
      Cnd1; non-SMC mitotic condensation complex subunit 1

    RNA

    1. XR_004935607.1 RNA Sequence

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