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    Uvrag UV radiation resistance associated gene [ Mus musculus (house mouse) ]

    Gene ID: 78610, updated on 23-Jun-2021

    Summary

    Official Symbol
    Uvragprovided by MGI
    Official Full Name
    UV radiation resistance associated geneprovided by MGI
    Primary source
    MGI:MGI:1925860
    See related
    Ensembl:ENSMUSG00000035354
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Uv; Uvrag1; Uvragl; AI648770; BB124205; 9530039D02Rik
    Expression
    Ubiquitous expression in spleen adult (RPKM 13.8), thymus adult (RPKM 12.8) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Uvrag in Genome Data Viewer
    Location:
    7; 7 E1
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (98535949..98790373, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (98886742..99141167, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (106035253..106289654, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 33770 Neighboring gene wingless-type MMTV integration site family, member 11 Neighboring gene predicted gene, 33827 Neighboring gene predicted gene 8149 Neighboring gene predicted gene, 23479 Neighboring gene predicted gene, 33882 Neighboring gene diacylglycerol O-acyltransferase 2 Neighboring gene monoacylglycerol O-acyltransferase 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables SH3 domain binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables SNARE binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables SNARE binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in DNA repair IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in DNA repair ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in SNARE complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within SNARE complex assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in autophagosome maturation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in autophagy ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within cellular response to DNA damage stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in centrosome cycle IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in centrosome cycle ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in chromosome segregation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in double-strand break repair via classical nonhomologous end joining ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in maintenance of Golgi location ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in receptor catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of cytokinesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of protein serine/threonine kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in spindle organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within viral entry into host cell IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of DNA-dependent protein kinase complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in autophagosome membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromosome, centromeric region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in early endosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in late endosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lysosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in lytic vacuole IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in midbody ISO
    Inferred from Sequence Orthology
    more info
     
    located_in phagocytic vesicle IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    part_of protein-containing complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    UV radiation resistance-associated protein
    Names
    UV radiation resistance associated protein
    UV radiation resistance-associated gene protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_178635.3NP_848750.3  UV radiation resistance-associated protein

      See identical proteins and their annotated locations for NP_848750.3

      Status: VALIDATED

      Source sequence(s)
      AK030814, AK078085, BB530952, BY024873
      Consensus CDS
      CCDS21476.1
      UniProtKB/Swiss-Prot
      Q8K245
      Related
      ENSMUSP00000045297.9, ENSMUST00000037968.10
      Conserved Domains (2) summary
      cd00030
      Location:44118
      C2; C2 domain
      pfam10186
      Location:183441
      Atg14; Vacuolar sorting 38 and autophagy-related subunit 14

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      98535949..98790373 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006508349.4XP_006508412.1  UV radiation resistance-associated protein isoform X1

      Conserved Domains (1) summary
      pfam10186
      Location:140398
      Atg14; Vacuolar sorting 38 and autophagy-related subunit 14
    2. XM_030243116.2XP_030098976.1  UV radiation resistance-associated protein isoform X2

      Conserved Domains (1) summary
      pfam10186
      Location:4173
      Atg14; Vacuolar sorting 38 and autophagy-related subunit 14
    3. XM_036153589.1XP_036009482.1  UV radiation resistance-associated protein isoform X2

      Conserved Domains (1) summary
      pfam10186
      Location:4173
      Atg14; Vacuolar sorting 38 and autophagy-related subunit 14
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