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    Srbd1 S1 RNA binding domain 1 [ Mus musculus (house mouse) ]

    Gene ID: 78586, updated on 31-Jan-2019

    Summary

    Official Symbol
    Srbd1provided by MGI
    Official Full Name
    S1 RNA binding domain 1provided by MGI
    Primary source
    MGI:MGI:1925836
    See related
    Ensembl:ENSMUSG00000024135
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C85414; AI461933; D530025C17Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 1.0), CNS E14 (RPKM 0.7) and 25 other tissues See more
    Orthologs

    Genomic context

    See Srbd1 in Genome Data Viewer
    Location:
    17; 17 E4
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (85984665..86145216, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (86384005..86544515, complement)

    Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene predicted gene 29418 Neighboring gene predicted gene, 30117 Neighboring gene protein kinase C, epsilon Neighboring gene RIKEN cDNA 2010106C02 gene Neighboring gene predicted gene, 30284

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Homology

    Clone Names

    • MGC117756, MGC198776

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    nucleobase-containing compound metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    cellular_component ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    S1 RNA-binding domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_030133.3NP_084409.3  S1 RNA-binding domain-containing protein 1

      Status: VALIDATED

      Source sequence(s)
      AC154185, AC154542
      Consensus CDS
      CCDS50204.1
      UniProtKB/TrEMBL
      F8WGW3
      Related
      ENSMUSP00000092810.3, ENSMUST00000095187.3
      Conserved Domains (5) summary
      COG2183
      Location:205978
      Tex; Transcriptional accessory protein Tex/SPT6 [Transcription]
      cd05685
      Location:905976
      S1_Tex; S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression. ...
      pfam09371
      Location:214409
      Tex_N; Tex-like protein N-terminal domain
      pfam12836
      Location:700762
      HHH_3; Helix-hairpin-helix motif
      pfam16921
      Location:533658
      Tex_YqgF; Tex protein YqgF-like domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

      Range
      85984665..86145216 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011246728.1XP_011245030.1  S1 RNA-binding domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_011245030.1

      Conserved Domains (5) summary
      COG2183
      Location:205992
      Tex; Transcriptional accessory protein Tex/SPT6 [Transcription]
      cd05685
      Location:919990
      S1_Tex; S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression. ...
      pfam09371
      Location:214409
      Tex_N; Tex-like protein N-terminal domain
      pfam12836
      Location:700762
      HHH_3; Helix-hairpin-helix motif
      pfam16921
      Location:533658
      Tex_YqgF; Tex protein YqgF-like domain
    2. XM_011246731.2XP_011245033.1  S1 RNA-binding domain-containing protein 1 isoform X4

      Conserved Domains (4) summary
      COG2183
      Location:21615
      Tex; Transcriptional accessory protein Tex/SPT6 [Transcription]
      cd05685
      Location:542613
      S1_Tex; S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression. ...
      pfam12836
      Location:323385
      HHH_3; Helix-hairpin-helix motif
      pfam16921
      Location:156281
      Tex_YqgF; Tex protein YqgF-like domain
    3. XM_017317728.1XP_017173217.1  S1 RNA-binding domain-containing protein 1 isoform X2

    4. XM_011246730.2XP_011245032.1  S1 RNA-binding domain-containing protein 1 isoform X3

      Conserved Domains (2) summary
      pfam09371
      Location:214409
      Tex_N; Tex-like protein N-terminal domain
      cl21482
      Location:533621
      RuvC_resolvase; Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD includes ...

    RNA

    1. XR_385394.3 RNA Sequence

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