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    Phf23 PHD finger protein 23 [ Mus musculus (house mouse) ]

    Gene ID: 78246, updated on 23-May-2018

    Summary

    Official Symbol
    Phf23provided by MGI
    Official Full Name
    PHD finger protein 23provided by MGI
    Primary source
    MGI:MGI:1925496
    See related
    Ensembl:ENSMUSG00000018572 Vega:OTTMUSG00000006021
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    JUNE-1
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 16.3), limb E14.5 (RPKM 10.2) and 28 other tissues See more
    Orthologs

    Genomic context

    See Phf23 in Genome Data Viewer
    Location:
    11 B3; 11
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (69995766..70000011)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (69809273..69813513)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene elongator acetyltransferase complex subunit 5 Neighboring gene CTD nuclear envelope phosphatase 1 Neighboring gene gamma-aminobutyric acid receptor associated protein Neighboring gene dishevelled segment polarity protein 2 Neighboring gene acyl-Coenzyme A dehydrogenase, very long chain Neighboring gene microRNA 324

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Homology

    Clone Names

    • 2410141M05Rik

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    autophagy IEA
    Inferred from Electronic Annotation
    more info
     
    mitotic chromosome condensation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    negative regulation of autophagosome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    negative regulation of autophagosome assembly ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of autophagosome maturation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    negative regulation of autophagosome maturation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of protein ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of protein ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    PHD finger protein 23
    Names
    PHD zinc finger containing protein JUNE1
    novel PHD-finger protein JUNE1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001291125.1NP_001278054.1  PHD finger protein 23 isoform b

      See identical proteins and their annotated locations for NP_001278054.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the central coding region, compared to variant 1. The encoded isoform (b) is shorter, compared to isoform a.
      Source sequence(s)
      AK031159, AL596185, AY099327, BY632579, CA750740
      Consensus CDS
      CCDS70223.1
      UniProtKB/Swiss-Prot
      Q8BSN5
      Related
      ENSMUSP00000099064.2, OTTMUSP00000006256, ENSMUST00000101526.8, OTTMUST00000013499
      Conserved Domains (1) summary
      cd15631
      Location:272315
      PHD_PHF23; PHD finger found in PHD finger protein 23 (PHF23)
    2. NM_001291126.1NP_001278055.1  PHD finger protein 23 isoform c

      See identical proteins and their annotated locations for NP_001278055.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in its 5' UTR and uses a downstream start codon, compared to variant 1. The encoded isoform (c) has a shorter N-terminus, compared to isoform a. Both variants 3 and 4 encode the same isoform.
      Source sequence(s)
      AK029376, BY262829, BY632579
      Consensus CDS
      CCDS78976.1
      UniProtKB/Swiss-Prot
      Q8BSN5
      Related
      ENSMUSP00000121780.1, OTTMUSP00000041051, ENSMUST00000153684.7, OTTMUST00000013500
      Conserved Domains (1) summary
      cd15631
      Location:209252
      PHD_PHF23; PHD finger found in PHD finger protein 23 (PHF23)
    3. NM_001291127.1NP_001278056.1  PHD finger protein 23 isoform c

      See identical proteins and their annotated locations for NP_001278056.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in its 5' UTR and uses a downstream start codon, compared to variant 1. The encoded isoform (c) has a shorter N-terminus, compared to isoform a. Both variants 3 and 4 encode the same isoform.
      Source sequence(s)
      AK029376, AL596185, BM947867, BY632579
      Consensus CDS
      CCDS78976.1
      UniProtKB/Swiss-Prot
      Q8BSN5
      Related
      ENSMUSP00000120665.1, OTTMUSP00000041052, ENSMUST00000135814.1, OTTMUST00000013503
      Conserved Domains (1) summary
      cd15631
      Location:209252
      PHD_PHF23; PHD finger found in PHD finger protein 23 (PHF23)
    4. NM_030064.4NP_084340.2  PHD finger protein 23 isoform a

      See identical proteins and their annotated locations for NP_084340.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).
      Source sequence(s)
      AK031159, AL596185, AY099326, BY632579, CA750740
      Consensus CDS
      CCDS24929.1
      UniProtKB/Swiss-Prot
      Q8BSN5
      Related
      ENSMUSP00000018716.3, OTTMUSP00000006255, ENSMUST00000018716.9, OTTMUST00000013498
      Conserved Domains (1) summary
      cd15631
      Location:339382
      PHD_PHF23; PHD finger found in PHD finger protein 23 (PHF23)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      69995766..70000011
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006534501.2XP_006534564.1  PHD finger protein 23 isoform X1

      See identical proteins and their annotated locations for XP_006534564.1

      Conserved Domains (1) summary
      cd15631
      Location:369412
      PHD_PHF23; PHD finger found in PHD finger protein 23 (PHF23)
    2. XM_006534502.2XP_006534565.2  PHD finger protein 23 isoform X2

      See identical proteins and their annotated locations for XP_006534565.2

      UniProtKB/Swiss-Prot
      Q8BSN5
      Conserved Domains (1) summary
      cd15631
      Location:209252
      PHD_PHF23; PHD finger found in PHD finger protein 23 (PHF23)

    Reference GRCm38.p4 NOD/MrkTac

    Genomic

    1. NT_187026.1 Reference GRCm38.p4 NOD/MrkTac

      Range
      100254..104498
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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