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    Trappc6b trafficking protein particle complex 6B [ Mus musculus (house mouse) ]

    Gene ID: 78232, updated on 18-Nov-2018

    Summary

    Official Symbol
    Trappc6bprovided by MGI
    Official Full Name
    trafficking protein particle complex 6Bprovided by MGI
    Primary source
    MGI:MGI:1925482
    See related
    Ensembl:ENSMUSG00000020993
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C79212; 5830498C14Rik
    Expression
    Ubiquitous expression in adrenal adult (RPKM 28.5), CNS E18 (RPKM 27.0) and 28 other tissues See more
    Orthologs

    Genomic context

    See Trappc6b in Genome Data Viewer
    Location:
    12; 12 C1
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 12 NC_000078.6 (59043092..59061472, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (60144079..60162448, complement)

    Chromosome 12 - NC_000078.6Genomic Context describing neighboring genes Neighboring gene SEC23 homolog A, COPII coat complex component Neighboring gene gem nuclear organelle associated protein 2 Neighboring gene pinin Neighboring gene ribosomal protein S2 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    ER to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Golgi vesicle transport IEA
    Inferred from Electronic Annotation
    more info
     
    nervous system development IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    cis-Golgi network IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    trans-Golgi network IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    trafficking protein particle complex subunit 6B
    Names
    TRAPP complex subunit 6B

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001306217.1NP_001293146.1  trafficking protein particle complex subunit 6B isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate exon in the 3' coding region, resulting in a frameshift, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus compared to isoform 1.
      Source sequence(s)
      AK020026, CO039101, DV660612
      UniProtKB/Swiss-Prot
      Q9D289
      UniProtKB/TrEMBL
      A0A1W2P7S5
      Related
      ENSMUSP00000151772.1, ENSMUST00000217863.1
      Conserved Domains (1) summary
      cd14944
      Location:3117
      TRAPPC6A_Trs33; Trs33 subunit of the TRAPP complex
    2. NM_001306218.1NP_001293147.1  trafficking protein particle complex subunit 6B isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) contains an alternate exon in its 5' UTR and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (3) has a shorter N-terminus compared to isoform 1.
      Source sequence(s)
      AC153654, AK020026, CO039101, DV660612
      UniProtKB/Swiss-Prot
      Q9D289
      Conserved Domains (1) summary
      cd14944
      Location:1118
      TRAPPC6A_Trs33; Trs33 subunit of the TRAPP complex
    3. NM_030057.3NP_084333.1  trafficking protein particle complex subunit 6B isoform 1

      See identical proteins and their annotated locations for NP_084333.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AK020026, CO039101, DV660612
      Consensus CDS
      CCDS25932.1
      UniProtKB/Swiss-Prot
      Q9D289
      Related
      ENSMUSP00000021380.8, ENSMUST00000021380.9
      Conserved Domains (1) summary
      cd14944
      Location:3156
      TRAPPC6A_Trs33; Trs33 subunit of the TRAPP complex

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000078.6 Reference GRCm38.p4 C57BL/6J

      Range
      59043092..59061472 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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