Format

Send to:

Choose Destination
    • Showing Current items.

    Ddx10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [ Mus musculus (house mouse) ]

    Gene ID: 77591, updated on 31-Jan-2019

    Summary

    Official Symbol
    Ddx10provided by MGI
    Official Full Name
    DEAD (Asp-Glu-Ala-Asp) box polypeptide 10provided by MGI
    Primary source
    MGI:MGI:1924841
    See related
    Ensembl:ENSMUSG00000053289
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI646054; 4632415A01Rik
    Expression
    Broad expression in CNS E11.5 (RPKM 4.2), liver E14 (RPKM 2.9) and 22 other tissues See more
    Orthologs

    Genomic context

    See Ddx10 in Genome Data Viewer
    Location:
    9; 9 A5.3
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (53098454..53248170, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (52906559..53056217, complement)

    Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene predicted gene 1715 Neighboring gene predicted gene, 33256 Neighboring gene predicted gene, 39339 Neighboring gene exophilin 5 Neighboring gene microRNA 130c Neighboring gene KDEL (Lys-Asp-Glu-Leu) containing 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC91294

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    helicase activity IEA
    Inferred from Electronic Annotation
    more info
     
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    anterior head development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 

    General protein information

    Preferred Names
    probable ATP-dependent RNA helicase DDX10
    Names
    DEAD box protein 10
    DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 10 (RNA helicase)
    NP_084212.2
    XP_006510747.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029936.2NP_084212.2  probable ATP-dependent RNA helicase DDX10

      See identical proteins and their annotated locations for NP_084212.2

      Status: VALIDATED

      Source sequence(s)
      AC112956, AC160139
      Consensus CDS
      CCDS52796.1
      UniProtKB/Swiss-Prot
      Q80Y44
      Related
      ENSMUSP00000065198.6, ENSMUST00000065630.7
      Conserved Domains (4) summary
      PRK04837
      Location:69450
      PRK04837; ATP-dependent RNA helicase RhlB; Provisional
      cd00079
      Location:288418
      HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
      cd00268
      Location:71275
      DEADc; DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif ...
      pfam13959
      Location:451510
      DUF4217; Domain of unknown function (DUF4217)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

      Range
      53098454..53248170 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006510684.3XP_006510747.1  probable ATP-dependent RNA helicase DDX10 isoform X1

      Conserved Domains (3) summary
      COG0513
      Location:50440
      SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]
      cd00079
      Location:288418
      HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
      cd00268
      Location:71275
      DEADc; DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif ...
    Support Center