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    Rab35 RAB35, member RAS oncogene family [ Mus musculus (house mouse) ]

    Gene ID: 77407, updated on 12-Aug-2018

    Summary

    Official Symbol
    Rab35provided by MGI
    Official Full Name
    RAB35, member RAS oncogene familyprovided by MGI
    Primary source
    MGI:MGI:1924657
    See related
    Ensembl:ENSMUSG00000029518 Vega:OTTMUSG00000014704
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    RAY; H-ray; RAB1C; AU040256; 9530019H02Rik
    Expression
    Ubiquitous expression in thymus adult (RPKM 51.4), adrenal adult (RPKM 39.3) and 28 other tissues See more
    Orthologs

    Genomic context

    See Rab35 in Genome Data Viewer
    Location:
    5; 5 F
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (115631899..115647158)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (116081996..116097167)

    Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene GCN1 general control of amino-acid synthesis 1-like 1 (yeast) Neighboring gene microRNA 7029 Neighboring gene RIKEN cDNA 1110006O24 gene Neighboring gene microRNA 7030 Neighboring gene BICD family like cargo adaptor 1 Neighboring gene ribosomal protein L29

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    GDP binding ISO
    Inferred from Sequence Orthology
    more info
     
    GTP binding ISO
    Inferred from Sequence Orthology
    more info
     
    GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    phosphatidylinositol-4,5-bisphosphate binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    Rab protein signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    antigen processing and presentation ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to nerve growth factor stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    endocytic recycling IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    endosomal transport ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitotic cytokinesis ISO
    Inferred from Sequence Orthology
    more info
     
    neuron projection development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    plasma membrane to endosome transport ISO
    Inferred from Sequence Orthology
    more info
     
    protein localization ISO
    Inferred from Sequence Orthology
    more info
     
    protein localization to endosome ISO
    Inferred from Sequence Orthology
    more info
     
    protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    anchored component of synaptic vesicle membrane ISO
    Inferred from Sequence Orthology
    more info
     
    cell projection membrane ISO
    Inferred from Sequence Orthology
    more info
     
    clathrin-coated endocytic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    clathrin-coated pit ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    endosome IEA
    Inferred from Electronic Annotation
    more info
     
    endosome membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    endosome membrane ISO
    Inferred from Sequence Orthology
    more info
     
    intercellular bridge ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrion HDA PubMed 
    plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ras-related protein Rab-35
    NP_937806.1
    XP_006530563.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_198163.1NP_937806.1  ras-related protein Rab-35

      See identical proteins and their annotated locations for NP_937806.1

      Status: PROVISIONAL

      Source sequence(s)
      BC056466
      Consensus CDS
      CCDS19596.1
      UniProtKB/Swiss-Prot
      Q6PHN9
      UniProtKB/TrEMBL
      Q3U0T9
      Related
      ENSMUSP00000031492.8, OTTMUSP00000015590, ENSMUST00000031492.14, OTTMUST00000034877
      Conserved Domains (1) summary
      cd04110
      Location:3201
      Rab35; Rab GTPase family 35 (Rab35)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

      Range
      115631899..115647158
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006530500.3XP_006530563.1  ras-related protein Rab-35 isoform X1

      Conserved Domains (1) summary
      cl21455
      Location:3117
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
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