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    Rab35 RAB35, member RAS oncogene family [ Mus musculus (house mouse) ]

    Gene ID: 77407, updated on 22-Aug-2021

    Summary

    Official Symbol
    Rab35provided by MGI
    Official Full Name
    RAB35, member RAS oncogene familyprovided by MGI
    Primary source
    MGI:MGI:1924657
    See related
    Ensembl:ENSMUSG00000029518
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    H-r; RAB; RAY; H-ray; RAB1C; AU040256; 9530019H02Rik
    Expression
    Ubiquitous expression in thymus adult (RPKM 51.4), adrenal adult (RPKM 39.3) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Rab35 in Genome Data Viewer
    Location:
    5; 5 F
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (115769953..115785217)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (115631904..115647158)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (116081996..116097167)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene GCN1 activator of EIF2AK4 Neighboring gene microRNA 7029 Neighboring gene RIKEN cDNA 1110006O24 gene Neighboring gene microRNA 7030 Neighboring gene BICD family like cargo adaptor 1 Neighboring gene ribosomal protein L29

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GDP binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables GTP binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphatidylinositol-4,5-bisphosphate binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in Rab protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in antigen processing and presentation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular response to nerve growth factor stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in endocytic recycling IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in endosomal transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitotic cytokinesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in neuron projection development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in plasma membrane to endosome transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein localization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein localization to endosome ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cell projection membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in clathrin-coated endocytic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in clathrin-coated pit ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in endosome membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in endosome membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in intercellular bridge ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion HDA PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ras-related protein Rab-35
    NP_937806.1
    XP_006530563.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_198163.1NP_937806.1  ras-related protein Rab-35

      See identical proteins and their annotated locations for NP_937806.1

      Status: PROVISIONAL

      Source sequence(s)
      BC056466
      Consensus CDS
      CCDS19596.1
      UniProtKB/Swiss-Prot
      Q6PHN9
      UniProtKB/TrEMBL
      Q3U0T9
      Related
      ENSMUSP00000031492.9, ENSMUST00000031492.15
      Conserved Domains (1) summary
      cd04110
      Location:3201
      Rab35; Rab GTPase family 35 (Rab35)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      115769953..115785217
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006530500.5XP_006530563.1  ras-related protein Rab-35 isoform X1

      Conserved Domains (1) summary
      cl38936
      Location:3117
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
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