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    Nkrf NF-kappaB repressing factor [ Mus musculus (house mouse) ]

    Gene ID: 77286, updated on 23-Jun-2021

    Summary

    Official Symbol
    Nkrfprovided by MGI
    Official Full Name
    NF-kappaB repressing factorprovided by MGI
    Primary source
    MGI:MGI:1924536
    See related
    Ensembl:ENSMUSG00000044149
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C80287; AW124770; 9430034D17Rik
    Expression
    Broad expression in cerebellum adult (RPKM 4.4), frontal lobe adult (RPKM 3.5) and 22 other tissues See more
    Orthologs
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    Genomic context

    See Nkrf in Genome Data Viewer
    Location:
    X; X A3.3
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (36149644..36167118, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (36885991..36903465, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (34427535..34442894, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene STING1 ER exit protein 1 Neighboring gene 60S ribosomal protein L39 pseudogene Neighboring gene ubiquitin-conjugating enzyme E2A Neighboring gene predicted gene 15008 Neighboring gene septin 6 Neighboring gene sosondowah ankyrin repeat domain family member D

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    NF-kappa-B-repressing factor
    Names
    NFkB-repressing factor
    transcription factor NRF

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029891.3NP_084167.3  NF-kappa-B-repressing factor

      Status: VALIDATED

      Source sequence(s)
      AL450399
      Consensus CDS
      CCDS30065.1
      Related
      ENSMUSP00000159216.2, ENSMUST00000239259.2
      Conserved Domains (4) summary
      cd02640
      Location:697756
      R3H_NRF; R3H domain of the NF-kappaB-repression factor (NRF). NRF is a nuclear inhibitor of NF-kappaB proteins that can silence the IFNbeta promoter via binding to a negative regulatory element (NRE). Beside R3H NRF also contains a G-patch domain. The name of the ...
      pfam11952
      Location:38105
      XTBD; XRN-Two Binding Domain, XTBD
      cl00054
      Location:543605
      DSRM_SF; double-stranded RNA binding motif (DSRM) superfamily
      cl02611
      Location:643686
      G-patch; G-patch domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      36149644..36167118 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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