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    2700049A03Rik RIKEN cDNA 2700049A03 gene [ Mus musculus (house mouse) ]

    Gene ID: 76967, updated on 31-Jan-2019

    Summary

    Official Symbol
    2700049A03Rikprovided by MGI
    Official Full Name
    RIKEN cDNA 2700049A03 geneprovided by MGI
    Primary source
    MGI:MGI:1924217
    See related
    Ensembl:ENSMUSG00000034601
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ta3; Talpid3; mKIAA0586
    Expression
    Broad expression in testis adult (RPKM 9.4), CNS E14 (RPKM 3.4) and 23 other tissues See more
    Orthologs

    Genomic context

    See 2700049A03Rik in Genome Data Viewer
    Location:
    12; 12 C2-C3
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 12 NC_000078.6 (71136848..71309964)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (72237835..72344290)

    Chromosome 12 - NC_000078.6Genomic Context describing neighboring genes Neighboring gene translocase of outer mitochondrial membrane 20-like Neighboring gene predicted gene, 32906 Neighboring gene translocase of inner mitochondrial membrane 9 Neighboring gene eukaryotic translation elongation factor 1 alpha 1 pseudogene Neighboring gene predicted gene 7959 Neighboring gene dishevelled-binding antagonist of beta-catenin 1 Neighboring gene predicted gene, 33016 Neighboring gene predicted gene, 40438

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Homology

    Clone Names

    • MGC183655

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    cell projection organization IEA
    Inferred from Electronic Annotation
    more info
     
    cilium assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cilium assembly ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    regulation of establishment of protein localization ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    smoothened signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    smoothened signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    centriole IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    centrosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    centrosome ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    ciliary basal body IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ciliary basal body ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163378.1NP_001156850.1  protein TALPID3 isoform 1

      See identical proteins and their annotated locations for NP_001156850.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      BC043104
      Consensus CDS
      CCDS49081.1
      UniProtKB/Swiss-Prot
      E9PV87
      Related
      ENSMUSP00000118956.1, ENSMUST00000149564.7
      Conserved Domains (2) summary
      pfam15324
      Location:1161347
      TALPID3; Hedgehog signalling target
      cl01860
      Location:259311
      DUF436; Protein of unknown function (DUF436)
    2. NM_029818.1NP_084094.1  protein TALPID3 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks two in-frame exons in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2) compared to isoform 1.
      Source sequence(s)
      BC043104
      Consensus CDS
      CCDS49082.1
      UniProtKB/TrEMBL
      E9Q0E2
      Related
      ENSMUSP00000044701.8, ENSMUST00000045907.15
      Conserved Domains (2) summary
      pfam15324
      Location:1161347
      TALPID3; Hedgehog signalling target
      cl01860
      Location:259311
      DUF436; Protein of unknown function (DUF436)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000078.6 Reference GRCm38.p4 C57BL/6J

      Range
      71136848..71309964
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006516364.2XP_006516427.1  protein TALPID3 isoform X1

      Conserved Domains (2) summary
      pfam15324
      Location:1161293
      TALPID3; Hedgehog signalling target
      cl01860
      Location:259311
      DUF436; Protein of unknown function (DUF436)
    2. XM_006516365.3XP_006516428.1  protein TALPID3 isoform X2

      Conserved Domains (2) summary
      pfam15324
      Location:1161347
      TALPID3; Hedgehog signalling target
      cl01860
      Location:259311
      DUF436; Protein of unknown function (DUF436)
    3. XM_006516366.3XP_006516429.1  protein TALPID3 isoform X4

      Conserved Domains (2) summary
      pfam15324
      Location:116984
      TALPID3; Hedgehog signalling target
      cl01860
      Location:259311
      DUF436; Protein of unknown function (DUF436)
    4. XM_011244208.1XP_011242510.1  protein TALPID3 isoform X3

      Conserved Domains (2) summary
      pfam15324
      Location:11206
      TALPID3; Hedgehog signalling target
      cl01860
      Location:118170
      DUF436; Protein of unknown function (DUF436)

    RNA

    1. XR_001780505.1 RNA Sequence

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