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    Memo1 mediator of cell motility 1 [ Mus musculus (house mouse) ]

    Gene ID: 76890, updated on 8-Oct-2018

    Summary

    Official Symbol
    Memo1provided by MGI
    Official Full Name
    mediator of cell motility 1provided by MGI
    Primary source
    MGI:MGI:1924140
    See related
    Ensembl:ENSMUSG00000058704
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    0610016J10Rik; D930048L02Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 11.5), liver E14 (RPKM 11.0) and 28 other tissues See more
    Orthologs

    Genomic context

    See Memo1 in Genome Data Viewer
    Location:
    17; 17 E2
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (74199043..74295529, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (74600040..74694203, complement)

    Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 31084 Neighboring gene predicted gene, 31235 Neighboring gene F-box protein 34 pseudogene Neighboring gene dpy-30, histone methyltransferase complex regulatory subunit Neighboring gene myeloma-overexpressed gene 2 protein homolog

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (4)  1 citation
    • Chemically induced (ENU) (1) 

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    peptide binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Process Evidence Code Pubs
    regulation of microtubule-based process ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    protein MEMO1
    Names
    mediator of ErbB2-driven cell motility 1
    memo-1
    protein memo

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_133771.2NP_598532.1  protein MEMO1

      See identical proteins and their annotated locations for NP_598532.1

      Status: VALIDATED

      Source sequence(s)
      AF363447, BF466279, CT010445
      Consensus CDS
      CCDS28969.1
      UniProtKB/Swiss-Prot
      Q91VH6
      Related
      ENSMUSP00000156607.1, ENSMUST00000233514.1
      Conserved Domains (1) summary
      cd07361
      Location:9294
      MEMO_like; Memo (mediator of ErbB2-driven cell motility) is co-precipitated with the C terminus of ErbB2, a protein involved in cell motility

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

      Range
      74199043..74295529 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006525109.3XP_006525172.1  protein MEMO1 isoform X1

      See identical proteins and their annotated locations for XP_006525172.1

      UniProtKB/Swiss-Prot
      Q91VH6
      Conserved Domains (1) summary
      cd07361
      Location:9294
      MEMO_like; Memo (mediator of ErbB2-driven cell motility) is co-precipitated with the C terminus of ErbB2, a protein involved in cell motility
    2. XM_011246713.2XP_011245015.1  protein MEMO1 isoform X2

      See identical proteins and their annotated locations for XP_011245015.1

      Conserved Domains (1) summary
      cl00599
      Location:114198
      Extradiol_Dioxygenase_3B_like; Subunit B of Class III Extradiol ring-cleavage dioxygenases
    3. XM_011246712.2XP_011245014.1  protein MEMO1 isoform X2

      See identical proteins and their annotated locations for XP_011245014.1

      Conserved Domains (1) summary
      cl00599
      Location:114198
      Extradiol_Dioxygenase_3B_like; Subunit B of Class III Extradiol ring-cleavage dioxygenases

    RNA

    1. XR_385387.3 RNA Sequence

    2. XR_385390.3 RNA Sequence

    3. XR_876587.2 RNA Sequence

    4. XR_876585.2 RNA Sequence

    5. XR_001782128.1 RNA Sequence

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