Format

Send to:

Choose Destination
    • Showing Current items.

    Coq8b coenzyme Q8B [ Mus musculus (house mouse) ]

    Gene ID: 76889, updated on 22-Aug-2021

    Summary

    Official Symbol
    Coq8bprovided by MGI
    Official Full Name
    coenzyme Q8Bprovided by MGI
    Primary source
    MGI:MGI:1924139
    See related
    Ensembl:ENSMUSG00000003762
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Adck; Adck4; 0610012P18Rik
    Expression
    Ubiquitous expression in adrenal adult (RPKM 18.8), ovary adult (RPKM 9.9) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Coq8b in Genome Data Viewer
    Location:
    7; 7 A3
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (26928112..26957374)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (27228676..27257949)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (28018032..28042968)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene cDNA sequence BC024978 Neighboring gene microRNA 1191 Neighboring gene inositol 1,4,5-trisphosphate 3-kinase C Neighboring gene numb-like Neighboring gene ribosomal protein L14 pseudogene Neighboring gene latent transforming growth factor beta binding protein 4 Neighboring gene predicted gene, 30543

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Clone Names

    • MGC101983, MGC102655

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cerebellar Purkinje cell layer morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in ubiquinone biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in ubiquinone biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in extrinsic component of mitochondrial inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    atypical kinase COQ8B, mitochondrial
    Names
    aarF domain containing kinase 4
    aarF domain-containing protein kinase 4
    coenzyme Q protein 8B

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_133770.2NP_598531.2  atypical kinase COQ8B, mitochondrial

      See identical proteins and their annotated locations for NP_598531.2

      Status: VALIDATED

      Source sequence(s)
      AK002619, AK079366, AK137168, BB770607, BY202506
      Consensus CDS
      CCDS39847.1
      UniProtKB/TrEMBL
      E9QLB8
      Related
      ENSMUSP00000003860.7, ENSMUST00000003860.13
      Conserved Domains (1) summary
      cd13970
      Location:176425
      ABC1_ADCK3; Activator of bc1 complex (ABC1) kinases, also called aarF domain containing kinase 3

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      26928112..26957374
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006540422.4XP_006540485.1  atypical kinase COQ8B, mitochondrial isoform X1

      See identical proteins and their annotated locations for XP_006540485.1

      UniProtKB/TrEMBL
      E9QLB8
      Conserved Domains (1) summary
      cd13970
      Location:176425
      ABC1_ADCK3; Activator of bc1 complex (ABC1) kinases, also called aarF domain containing kinase 3
    2. XM_036153553.1XP_036009446.1  atypical kinase COQ8B, mitochondrial isoform X1

      Conserved Domains (1) summary
      cd13970
      Location:176425
      ABC1_ADCK3; Activator of bc1 complex (ABC1) kinases, also called aarF domain containing kinase 3
    3. XM_011250741.4XP_011249043.1  atypical kinase COQ8B, mitochondrial isoform X3

      Related
      ENSMUSP00000123309.2, ENSMUST00000128090.8
      Conserved Domains (1) summary
      cl21453
      Location:176299
      PKc_like; Protein Kinases, catalytic domain
    4. XM_017312382.3XP_017167871.1  atypical kinase COQ8B, mitochondrial isoform X2

      Conserved Domains (1) summary
      cd13970
      Location:17266
      ABC1_ADCK3; Activator of bc1 complex (ABC1) kinases, also called aarF domain containing kinase 3
    5. XM_006540421.2XP_006540484.1  atypical kinase COQ8B, mitochondrial isoform X1

      See identical proteins and their annotated locations for XP_006540484.1

      UniProtKB/TrEMBL
      E9QLB8
      Related
      ENSMUSP00000104015.4, ENSMUST00000108378.10
      Conserved Domains (1) summary
      cd13970
      Location:176425
      ABC1_ADCK3; Activator of bc1 complex (ABC1) kinases, also called aarF domain containing kinase 3

    RNA

    1. XR_391109.2 RNA Sequence

    2. XR_004934204.1 RNA Sequence

    Support Center