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    Nlrp14 NLR family, pyrin domain containing 14 [ Mus musculus (house mouse) ]

    Gene ID: 76858, updated on 31-Aug-2021

    Summary

    Official Symbol
    Nlrp14provided by MGI
    Official Full Name
    NLR family, pyrin domain containing 14provided by MGI
    Primary source
    MGI:MGI:1924108
    See related
    Ensembl:ENSMUSG00000016626
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Na; GC-; GC-LRR; Nalp14; Nalp14l; Nalp-iota; 4921520L01Rik
    Expression
    Restricted expression toward testis adult (RPKM 17.2) See more
    Orthologs
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    Genomic context

    See Nlrp14 in Genome Data Viewer
    Location:
    7; 7 E3
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (106712662..106797310)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (107113455..107198103)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (114310504..114341617)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor 17 Neighboring gene olfactory receptor 715B Neighboring gene olfactory receptor 715 Neighboring gene olfactory receptor 716 Neighboring gene PWP1 homolog pseudogene Neighboring gene RNA binding motif protein, X-linked-like 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in spermatogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    NACHT, LRR and PYD domains-containing protein 14
    Names
    NACHT, leucine rich repeat and PYD containing 14
    RNI-like protein
    germ-cell specific leucine rich repeat NTPase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002894.2NP_001002894.2  NACHT, LRR and PYD domains-containing protein 14

      See identical proteins and their annotated locations for NP_001002894.2

      Status: VALIDATED

      Source sequence(s)
      BC141199, CJ053047, DV644607
      Consensus CDS
      CCDS21688.1
      UniProtKB/Swiss-Prot
      Q6B966
      Related
      ENSMUSP00000081819.3, ENSMUST00000084763.5
      Conserved Domains (5) summary
      sd00033
      Location:637660
      LRR_RI; leucine-rich repeat [structural motif]
      pfam05729
      Location:82249
      NACHT; NACHT domain
      pfam17776
      Location:383500
      NLRC4_HD2; NLRC4 helical domain HD2
      pfam17779
      Location:326381
      NOD2_WH; NOD2 winged helix domain
      cl39015
      Location:635952
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      106712662..106797310
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011241938.2XP_011240240.1  NACHT, LRR and PYD domains-containing protein 14 isoform X1

      See identical proteins and their annotated locations for XP_011240240.1

      UniProtKB/Swiss-Prot
      Q6B966
      Conserved Domains (5) summary
      sd00033
      Location:637660
      LRR_RI; leucine-rich repeat [structural motif]
      pfam05729
      Location:82249
      NACHT; NACHT domain
      pfam17776
      Location:383500
      NLRC4_HD2; NLRC4 helical domain HD2
      pfam17779
      Location:326381
      NOD2_WH; NOD2 winged helix domain
      cl39015
      Location:635952
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
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