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    Mzt1 mitotic spindle organizing protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 76789, updated on 23-Jun-2021

    Summary

    Official Symbol
    Mzt1provided by MGI
    Official Full Name
    mitotic spindle organizing protein 1provided by MGI
    Primary source
    MGI:MGI:1924039
    See related
    Ensembl:ENSMUSG00000033186
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mozart1; AI120158; 2410129H14Rik
    Expression
    Broad expression in whole brain E14.5 (RPKM 17.8), CNS E18 (RPKM 17.4) and 25 other tissues See more
    Orthologs
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    Genomic context

    See Mzt1 in Genome Data Viewer
    Location:
    14; 14 E2.2
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (99271980..99283898, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (99034544..99046453, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (99433763..99445355, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein L36A, pseudogene 1 Neighboring gene VISTA enhancer mm829 Neighboring gene bora, aurora kinase A activator Neighboring gene DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease Neighboring gene progesterone immunomodulatory binding factor 1 Neighboring gene Kruppel-like factor 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in gamma-tubulin complex localization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in microtubule nucleation by interphase microtubule organizing center IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in mitotic spindle assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    part_of gamma-tubulin large complex ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in interphase microtubule organizing center IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in spindle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in spindle ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    mitotic-spindle organizing protein 1
    Names
    mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175245.4NP_780454.1  mitotic-spindle organizing protein 1

      See identical proteins and their annotated locations for NP_780454.1

      Status: VALIDATED

      Source sequence(s)
      AK151232, AK169036, BB844588
      Consensus CDS
      CCDS49554.1
      UniProtKB/Swiss-Prot
      Q8BUR9
      Related
      ENSMUSP00000037557.9, ENSMUST00000042662.10
      Conserved Domains (1) summary
      pfam12554
      Location:1964
      MOZART1; Mitotic-spindle organizing gamma-tubulin ring associated

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      99271980..99283898 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030248094.2XP_030103954.1  mitotic-spindle organizing protein 1 isoform X1

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