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    Mettl4 methyltransferase like 4 [ Mus musculus (house mouse) ]

    Gene ID: 76781, updated on 12-Aug-2018

    Summary

    Official Symbol
    Mettl4provided by MGI
    Official Full Name
    methyltransferase like 4provided by MGI
    Primary source
    MGI:MGI:1924031
    See related
    Ensembl:ENSMUSG00000055660
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    HsT661; AV296509; 2410198H06Rik; A730091E08Rik
    Expression
    Ubiquitous expression in CNS E14 (RPKM 3.7), CNS E11.5 (RPKM 3.4) and 25 other tissues See more
    Orthologs

    Genomic context

    See Mettl4 in Genome Data Viewer
    Location:
    17; 17 E5
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (94722658..94750172, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (95126420..95149232, complement)

    Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene predicted gene 9416 Neighboring gene predicted gene, 41655 Neighboring gene NDC80 homolog, kinetochore complex component pseudogene Neighboring gene predicted gene 1976 Neighboring gene S-adenosylmethionine decarboxylase, pseudogene 7 Neighboring gene signal recognition particle 19 kDa protein pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    site-specific DNA-methyltransferase (adenine-specific) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    biological_process ND
    No biological Data available
    more info
     
    methylation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    methyltransferase-like protein 4

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001357135.1NP_001344064.1  methyltransferase-like protein 4 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC165075, BE633059
      Conserved Domains (1) summary
      cl01947
      Location:280454
      MT-A70; MT-A70
    2. NM_001357136.1NP_001344065.1  methyltransferase-like protein 4 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC165075, BE633059
      Conserved Domains (1) summary
      cl01947
      Location:280454
      MT-A70; MT-A70
    3. NM_001357137.1NP_001344066.1  methyltransferase-like protein 4 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC165075, BE633059
      Conserved Domains (1) summary
      cl01947
      Location:259433
      MT-A70; MT-A70
    4. NM_001357138.1NP_001344067.1  methyltransferase-like protein 4 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC165075, BE633059
      Conserved Domains (1) summary
      cl01947
      Location:259433
      MT-A70; MT-A70
    5. NM_176917.5NP_795891.2  methyltransferase-like protein 4 isoform 1

      See identical proteins and their annotated locations for NP_795891.2

      Status: VALIDATED

      Source sequence(s)
      AC165075, BE633059
      Consensus CDS
      CCDS29030.1
      UniProtKB/Swiss-Prot
      Q3U034
      Related
      ENSMUSP00000127142.1, ENSMUST00000171284.1
      Conserved Domains (1) summary
      cl01947
      Location:280454
      MT-A70; MT-A70

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

      Range
      94722658..94750172 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006525106.3XP_006525169.1  methyltransferase-like protein 4 isoform X1

      UniProtKB/Swiss-Prot
      Q3U034
      Conserved Domains (1) summary
      cl01947
      Location:280454
      MT-A70; MT-A70
    2. XM_006525107.3XP_006525170.1  methyltransferase-like protein 4 isoform X3

      UniProtKB/TrEMBL
      A4FTY8
      Conserved Domains (1) summary
      cl01947
      Location:259433
      MT-A70; MT-A70
    3. XM_006525105.3XP_006525168.1  methyltransferase-like protein 4 isoform X1

      UniProtKB/Swiss-Prot
      Q3U034
      Conserved Domains (1) summary
      cl01947
      Location:280454
      MT-A70; MT-A70
    4. XM_017317719.1XP_017173208.1  methyltransferase-like protein 4 isoform X3

      UniProtKB/TrEMBL
      A4FTY8
      Conserved Domains (1) summary
      cl01947
      Location:259433
      MT-A70; MT-A70
    5. XM_017317720.1XP_017173209.1  methyltransferase-like protein 4 isoform X4

    6. XM_011246710.2XP_011245012.1  methyltransferase-like protein 4 isoform X2

      Conserved Domains (1) summary
      cl01947
      Location:280422
      MT-A70; MT-A70

    RNA

    1. XR_001782127.1 RNA Sequence

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