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    Creld2 cysteine-rich with EGF-like domains 2 [ Mus musculus (house mouse) ]

    Gene ID: 76737, updated on 23-Jun-2021

    Summary

    Official Symbol
    Creld2provided by MGI
    Official Full Name
    cysteine-rich with EGF-like domains 2provided by MGI
    Primary source
    MGI:MGI:1923987
    See related
    Ensembl:ENSMUSG00000023272
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C85758; 5730592L21Rik
    Expression
    Broad expression in testis adult (RPKM 146.2), ovary adult (RPKM 63.5) and 25 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Creld2 in Genome Data Viewer
    Location:
    15; 15 E3
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (88703849..88710884)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (88819646..88826681)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (88650076..88657111)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene zinc finger, BED type containing 4 Neighboring gene asparagine-linked glycosylation 12 (alpha-1,6-mannosyltransferase) Neighboring gene predicted gene, 23144 Neighboring gene predicted gene, 33049 Neighboring gene proviral integration site 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables extracellular matrix structural constituent RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein disulfide isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in extracellular space IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    protein disulfide isomerase Creld2
    Names
    cysteine-rich with EGF-like domain protein 2
    NP_083996.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029720.2NP_083996.1  protein disulfide isomerase Creld2 precursor

      See identical proteins and their annotated locations for NP_083996.1

      Status: PROVISIONAL

      Source sequence(s)
      AK017880
      Consensus CDS
      CCDS27733.1
      UniProtKB/Swiss-Prot
      Q9CYA0
      Related
      ENSMUSP00000024042.4, ENSMUST00000024042.5
      Conserved Domains (3) summary
      smart00261
      Location:253288
      FU; Furin-like repeats
      cd00064
      Location:196246
      FU; Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.
      cl00057
      Location:286326
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      88703849..88710884
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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