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    Mtif3 mitochondrial translational initiation factor 3 [ Mus musculus (house mouse) ]

    Gene ID: 76366, updated on 23-May-2018

    Summary

    Official Symbol
    Mtif3provided by MGI
    Official Full Name
    mitochondrial translational initiation factor 3provided by MGI
    Primary source
    MGI:MGI:1923616
    See related
    Ensembl:ENSMUSG00000016510 Vega:OTTMUSG00000024605
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI414549; 2810012L14Rik
    Expression
    Ubiquitous expression in kidney adult (RPKM 7.4), CNS E18 (RPKM 6.4) and 28 other tissues See more
    Orthologs

    Genomic context

    See Mtif3 in Genome Data Viewer
    Location:
    5; 5 G3
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (146951573..146963849, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (147766098..147775350, complement)

    Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene RAS-like, family 11, member A Neighboring gene predicted gene, 38748 Neighboring gene general transcription factor III A Neighboring gene predicted gene, 46936 Neighboring gene ligand of numb-protein X 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ribosomal small subunit binding ISO
    Inferred from Sequence Orthology
    more info
     
    ribosomal small subunit binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    ribosome binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    translation factor activity, RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    translation factor activity, RNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    translation initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    mitochondrial translational initiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitochondrial translational initiation ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrial translational initiation ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    ribosome disassembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ribosome disassembly ISO
    Inferred from Sequence Orthology
    more info
     
    ribosome disassembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    translation IEA
    Inferred from Electronic Annotation
    more info
     
    translational initiation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion TAS
    Traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    translation initiation factor IF-3, mitochondrial
    Names
    IF-3(Mt)
    IF-3Mt
    IF3(mt)
    IF3mt

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001256100.1NP_001243029.1  translation initiation factor IF-3, mitochondrial

      See identical proteins and their annotated locations for NP_001243029.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) is the longest transcript. All five variants encode the same protein.
      Source sequence(s)
      AK012733, BC052439, BC115685, BM944410, BY284518
      Consensus CDS
      CCDS19874.1
      UniProtKB/Swiss-Prot
      Q9CZD5
      UniProtKB/TrEMBL
      A4QMQ0
      Related
      ENSMUSP00000106193.1, OTTMUSP00000029494, ENSMUST00000110564.7, OTTMUST00000060472
      Conserved Domains (2) summary
      pfam05198
      Location:76143
      IF3_N; Translation initiation factor IF-3, N-terminal domain
      cl27649
      Location:62225
      IF3_C; Translation initiation factor IF-3, C-terminal domain
    2. NM_001256101.1NP_001243030.1  translation initiation factor IF-3, mitochondrial

      See identical proteins and their annotated locations for NP_001243030.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All five variants encode the same protein.
      Source sequence(s)
      AK012733, BC052439, BM944410, BY284518
      Consensus CDS
      CCDS19874.1
      UniProtKB/Swiss-Prot
      Q9CZD5
      UniProtKB/TrEMBL
      A4QMQ0
      Related
      ENSMUSP00000016654.2, OTTMUSP00000029491, ENSMUST00000016654.8, OTTMUST00000060469
      Conserved Domains (2) summary
      pfam05198
      Location:76143
      IF3_N; Translation initiation factor IF-3, N-terminal domain
      cl27649
      Location:62225
      IF3_C; Translation initiation factor IF-3, C-terminal domain
    3. NM_001256102.1NP_001243031.1  translation initiation factor IF-3, mitochondrial

      See identical proteins and their annotated locations for NP_001243031.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. All five variants encode the same protein.
      Source sequence(s)
      BC052439, BC115684, BC115685, BM944410, BY284518
      Consensus CDS
      CCDS19874.1
      UniProtKB/Swiss-Prot
      Q9CZD5
      UniProtKB/TrEMBL
      A4QMQ0
      Related
      ENSMUSP00000106195.1, OTTMUSP00000029493, ENSMUST00000110566.1, OTTMUST00000060471
      Conserved Domains (2) summary
      pfam05198
      Location:76143
      IF3_N; Translation initiation factor IF-3, N-terminal domain
      cl27649
      Location:62225
      IF3_C; Translation initiation factor IF-3, C-terminal domain
    4. NM_001359467.1NP_001346396.1  translation initiation factor IF-3, mitochondrial

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. All five variants encode the same protein.
      Source sequence(s)
      AC124828, AL513345
      Conserved Domains (2) summary
      pfam05198
      Location:76143
      IF3_N; Translation initiation factor IF-3, N-terminal domain
      cl27649
      Location:62225
      IF3_C; Translation initiation factor IF-3, C-terminal domain
    5. NM_029581.4NP_083857.1  translation initiation factor IF-3, mitochondrial

      See identical proteins and their annotated locations for NP_083857.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All five variants encode the same protein.
      Source sequence(s)
      AK147090, BC052439, BM944410, BY284518
      Consensus CDS
      CCDS19874.1
      UniProtKB/Swiss-Prot
      Q9CZD5
      UniProtKB/TrEMBL
      A4QMQ0
      Related
      ENSMUSP00000063398.3, OTTMUSP00000029492, ENSMUST00000066675.9, OTTMUST00000060470
      Conserved Domains (2) summary
      pfam05198
      Location:76143
      IF3_N; Translation initiation factor IF-3, N-terminal domain
      cl27649
      Location:62225
      IF3_C; Translation initiation factor IF-3, C-terminal domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

      Range
      146951573..146963849 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006504889.3XP_006504952.1  translation initiation factor IF-3, mitochondrial isoform X1

      UniProtKB/Swiss-Prot
      Q9CZD5
      UniProtKB/TrEMBL
      A4QMQ0
      Conserved Domains (2) summary
      pfam05198
      Location:76143
      IF3_N; Translation initiation factor IF-3, N-terminal domain
      cl27649
      Location:62225
      IF3_C; Translation initiation factor IF-3, C-terminal domain
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