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    Rab1b RAB1B, member RAS oncogene family [ Mus musculus (house mouse) ]

    Gene ID: 76308, updated on 5-Jul-2025
    Official Symbol
    Rab1bprovided by MGI
    Official Full Name
    RAB1B, member RAS oncogene familyprovided by MGI
    Primary source
    MGI:MGI:1923558
    See related
    Ensembl:ENSMUSG00000024870 AllianceGenome:MGI:1923558
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1110011F09Rik
    Summary
    Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in Golgi organization; autophagosome assembly; and intracellular protein transport. Located in endoplasmic reticulum-Golgi intermediate compartment. Is expressed in diaphragm. Orthologous to several human genes including RAB1B (RAB1B, member RAS oncogene family). [provided by Alliance of Genome Resources, Jul 2025]
    Expression
    Ubiquitous expression in subcutaneous fat pad adult (RPKM 59.5), genital fat pad adult (RPKM 55.0) and 28 other tissues See more
    Orthologs
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    See Rab1b in Genome Data Viewer
    Location:
    19 A; 19 4.25 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (5149235..5157024, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (5099207..5106996, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E1968 Neighboring gene uncharacterized LOC132660285 Neighboring gene STARR-positive B cell enhancer ABC_E7627 Neighboring gene transmembrane protein 151A Neighboring gene Yip1 interacting factor homolog A (S. cerevisiae) Neighboring gene cornichon family AMPA receptor auxiliary protein 2 Neighboring gene STARR-positive B cell enhancer ABC_E1969 Neighboring gene kinesin light chain 2 Neighboring gene predicted gene, 30840

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Gene trapped (1) 
    • Targeted (1) 
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTP binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables GTP binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in Golgi organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in Golgi organization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in autophagosome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in autophagy IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of glycoprotein metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of autophagosome assembly IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in virion assembly IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum-Golgi intermediate compartment IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion HDA PubMed 
    located_in perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in phagophore assembly site membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in phagophore assembly site membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in synapse ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    ras-related protein Rab-1B
    NP_083852.1

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029576.3NP_083852.1  ras-related protein Rab-1B

      See identical proteins and their annotated locations for NP_083852.1

      Status: VALIDATED

      Source sequence(s)
      AC124502
      Consensus CDS
      CCDS29452.1
      UniProtKB/Swiss-Prot
      Q3U0N1, Q9D1G1
      UniProtKB/TrEMBL
      Q0PD66, Q3V3C2
      Related
      ENSMUSP00000025804.6, ENSMUST00000025804.7
      Conserved Domains (1) summary
      cd01869
      Location:7172
      Rab1_Ypt1; Rab GTPase family 1 includes the yeast homolog Ypt1

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      5149235..5157024 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)