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    Tsen54 tRNA splicing endonuclease subunit 54 [ Mus musculus (house mouse) ]

    Gene ID: 76265, updated on 23-Jun-2021

    Summary

    Official Symbol
    Tsen54provided by MGI
    Official Full Name
    tRNA splicing endonuclease subunit 54provided by MGI
    Primary source
    MGI:MGI:1923515
    See related
    Ensembl:ENSMUSG00000020781
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    0610034P02Rik
    Expression
    Ubiquitous expression in duodenum adult (RPKM 11.3), ovary adult (RPKM 11.0) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Tsen54 in Genome Data Viewer
    Location:
    11; 11 E2
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (115704563..115713928)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (115813728..115823102)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (115676053..115684416)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene transmembrane protein 94 Neighboring gene microRNA 5621 Neighboring gene CASK-interacting protein 2 Neighboring gene LLGL2 scribble cell polarity complex component Neighboring gene myosin XVB Neighboring gene RecQ protein-like 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2)  1 citation
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    acts_upstream_of_or_within mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within tRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in tRNA splicing, via endonucleolytic cleavage and ligation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in tRNA-type intron splice site recognition and cleavage IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of tRNA-intron endonuclease complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    tRNA-splicing endonuclease subunit Sen54
    Names
    likely ortholog of H. sapiens SEN54L
    tRNA splicing endonuclease 54 homolog
    tRNA-intron endonuclease Sen54

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029557.1NP_083833.1  tRNA-splicing endonuclease subunit Sen54

      See identical proteins and their annotated locations for NP_083833.1

      Status: VALIDATED

      Source sequence(s)
      AK002758, BB273422, BY203746
      Consensus CDS
      CCDS25648.1
      UniProtKB/Swiss-Prot
      Q8C2A2
      Related
      ENSMUSP00000021134.4, ENSMUST00000021134.10
      Conserved Domains (1) summary
      pfam12928
      Location:63130
      tRNA_int_end_N2; tRNA-splicing endonuclease subunit sen54 N-term

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      115704563..115713928
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006534415.4XP_006534478.1  tRNA-splicing endonuclease subunit Sen54 isoform X1

      See identical proteins and their annotated locations for XP_006534478.1

      Conserved Domains (2) summary
      PRK09297
      Location:181252
      PRK09297; tRNA-splicing endonuclease subunit alpha; Reviewed
      pfam12928
      Location:128195
      tRNA_int_end_N2; tRNA-splicing endonuclease subunit sen54 N-term
    2. XM_006534419.4XP_006534482.1  tRNA-splicing endonuclease subunit Sen54 isoform X2

      Conserved Domains (2) summary
      PRK09297
      Location:181234
      PRK09297; tRNA-splicing endonuclease subunit alpha; Reviewed
      pfam12928
      Location:128195
      tRNA_int_end_N2; tRNA-splicing endonuclease subunit sen54 N-term
    3. XM_006534417.4XP_006534480.1  tRNA-splicing endonuclease subunit Sen54 isoform X1

      See identical proteins and their annotated locations for XP_006534480.1

      Conserved Domains (2) summary
      PRK09297
      Location:181252
      PRK09297; tRNA-splicing endonuclease subunit alpha; Reviewed
      pfam12928
      Location:128195
      tRNA_int_end_N2; tRNA-splicing endonuclease subunit sen54 N-term
    4. XM_036157059.1XP_036012952.1  tRNA-splicing endonuclease subunit Sen54 isoform X3

      Conserved Domains (2) summary
      pfam12928
      Location:81148
      tRNA_int_end_N2; tRNA-splicing endonuclease subunit sen54 N-term
      cl40623
      Location:134187
      tRNA_int_end_N2; tRNA-splicing endonuclease subunit sen54 N-term

    RNA

    1. XR_879757.4 RNA Sequence

    2. XR_004937055.1 RNA Sequence

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