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    Med13l mediator complex subunit 13-like [ Mus musculus (house mouse) ]

    Gene ID: 76199, updated on 23-Jun-2021

    Summary

    Official Symbol
    Med13lprovided by MGI
    Official Full Name
    mediator complex subunit 13-likeprovided by MGI
    Primary source
    MGI:MGI:2670178
    See related
    Ensembl:ENSMUSG00000018076
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Thr; Trap; Thrap2; Trap240L; mKIAA1025; 2210413I17Rik; 6330591G05Rik; 9030618F05Rik
    Expression
    Ubiquitous expression in thymus adult (RPKM 10.1), spleen adult (RPKM 6.5) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Med13l in Genome Data Viewer
    Location:
    5; 5 F
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (118698675..118903503)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (118560330..118765438)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (119010728..119215447)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene basic transcription factor 3, pseudogene 11 Neighboring gene predicted gene, 46921 Neighboring gene predicted gene, 42015 Neighboring gene RIKEN cDNA 4930413E15 gene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of mediator complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    mediator of RNA polymerase II transcription subunit 13-like
    Names
    thyroid hormone receptor associated protein 2
    thyroid hormone receptor-associated protein complex 240 kDa component-like

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001347445.1NP_001334374.1  mediator of RNA polymerase II transcription subunit 13-like isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC117585, AC129552
      Consensus CDS
      CCDS84948.1
      UniProtKB/TrEMBL
      A0A0J9YUA8
      Related
      ENSMUSP00000144092.2, ENSMUST00000201010.2
    2. NM_172424.4NP_766012.3  mediator of RNA polymerase II transcription subunit 13-like isoform 2

      See identical proteins and their annotated locations for NP_766012.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice junction compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
      Source sequence(s)
      AK018557, AK075850, AK142391, AY338464, BC072653, BQ748188
      Consensus CDS
      CCDS57375.1
      UniProtKB/Swiss-Prot
      Q6JPI3
      UniProtKB/TrEMBL
      E9QLJ3, Q6GQS5
      Related
      ENSMUSP00000098379.5, ENSMUST00000100816.8
      Conserved Domains (2) summary
      pfam06333
      Location:16752194
      Med13_C; Mediator complex subunit 13 C-terminal
      pfam11597
      Location:16380
      Med13_N; Mediator complex subunit 13 N-terminal

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      118698675..118903503
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030254882.2XP_030110742.1  mediator of RNA polymerase II transcription subunit 13-like isoform X2

      Conserved Domains (3) summary
      pfam06333
      Location:17922195
      Med13_C; Mediator complex subunit 13 C-terminal
      pfam11597
      Location:11287
      Med13_N; Mediator complex subunit 13 N-terminal
      pfam18296
      Location:14141756
      MID_MedPIWI; MID domain of medPIWI
    2. XM_011248248.4XP_011246550.1  mediator of RNA polymerase II transcription subunit 13-like isoform X1

      Conserved Domains (3) summary
      pfam06333
      Location:17922204
      Med13_C; Mediator complex subunit 13 C-terminal
      pfam11597
      Location:11287
      Med13_N; Mediator complex subunit 13 N-terminal
      pfam18296
      Location:14141756
      MID_MedPIWI; MID domain of medPIWI
    3. XM_036165591.1XP_036021484.1  mediator of RNA polymerase II transcription subunit 13-like isoform X3

      Conserved Domains (2) summary
      pfam06333
      Location:16592071
      Med13_C; Mediator complex subunit 13 C-terminal
      pfam18296
      Location:12811623
      MID_MedPIWI; MID domain of medPIWI
    4. XM_030254883.1XP_030110743.1  mediator of RNA polymerase II transcription subunit 13-like isoform X3

      Conserved Domains (2) summary
      pfam06333
      Location:16592071
      Med13_C; Mediator complex subunit 13 C-terminal
      pfam18296
      Location:12811623
      MID_MedPIWI; MID domain of medPIWI
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