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    Gon4l gon-4-like (C.elegans) [ Mus musculus (house mouse) ]

    Gene ID: 76022, updated on 2-Oct-2018

    Summary

    Official Symbol
    Gon4lprovided by MGI
    Official Full Name
    gon-4-like (C.elegans)provided by MGI
    Primary source
    MGI:MGI:1917579
    See related
    Ensembl:ENSMUSG00000054199 Vega:OTTMUSG00000022718
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AA387005; 1500041I23Rik; 2610100B20Rik; 3632445O20Rik; 5430404N14Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 18.1), CNS E14 (RPKM 12.6) and 28 other tissues See more
    Orthologs

    Genomic context

    See Gon4l in Genome Data Viewer
    Location:
    3; 3 F1
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 3 NC_000069.6 (88830966..88910099)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (88639150..88714021)

    Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene gon-4-like pseudogene Neighboring gene synaptotagmin XI Neighboring gene RIKEN cDNA 1500004A13 gene Neighboring gene predicted gene, 40091 Neighboring gene misato 1, mitochondrial distribution and morphology regulator Neighboring gene death associated protein 3 Neighboring gene ASH1 like histone lysine methyltransferase Neighboring gene RUN and SH3 domain containing 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    transcription corepressor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    B cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of transcription, DNA-templated IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    GON-4-like protein
    Names
    GON-4 homolog

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001242372.1NP_001229301.1  GON-4-like protein isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC127377, AK147575, BC108377
      UniProtKB/TrEMBL
      Q32NZ8
      Conserved Domains (2) summary
      cd12202
      Location:21612226
      CASP8AP2; Caspase 8-associated protein 2 myb-like domain
      pfam02671
      Location:16711716
      PAH; Paired amphipathic helix repeat
    2. NM_027389.3NP_081665.2  GON-4-like protein isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
      Source sequence(s)
      AC127377, AK147575, BC108377
      Consensus CDS
      CCDS50954.1
      UniProtKB/TrEMBL
      E9Q507, Q32NZ8
      Related
      ENSMUSP00000103122.2, OTTMUSP00000026021, ENSMUST00000107498.8, OTTMUST00000054494
      Conserved Domains (2) summary
      cd12202
      Location:21442209
      CASP8AP2; Caspase 8-associated protein 2 myb-like domain
      pfam02671
      Location:16541699
      PAH; Paired amphipathic helix repeat

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000069.6 Reference GRCm38.p4 C57BL/6J

      Range
      88830966..88910099
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006502240.3XP_006502303.1  GON-4-like protein isoform X1

      See identical proteins and their annotated locations for XP_006502303.1

      Conserved Domains (2) summary
      cd12202
      Location:21632228
      CASP8AP2; Caspase 8-associated protein 2 myb-like domain
      pfam02671
      Location:16721717
      PAH; Paired amphipathic helix repeat
    2. XM_006502237.3XP_006502300.1  GON-4-like protein isoform X1

      See identical proteins and their annotated locations for XP_006502300.1

      Conserved Domains (2) summary
      cd12202
      Location:21632228
      CASP8AP2; Caspase 8-associated protein 2 myb-like domain
      pfam02671
      Location:16721717
      PAH; Paired amphipathic helix repeat
    3. XM_017319793.1XP_017175282.1  GON-4-like protein isoform X2

      UniProtKB/Swiss-Prot
      Q9DB00
      Conserved Domains (2) summary
      cd12202
      Location:21622227
      CASP8AP2; Caspase 8-associated protein 2 myb-like domain
      pfam02671
      Location:16721717
      PAH; Paired amphipathic helix repeat
    4. XM_017319795.1XP_017175284.1  GON-4-like protein isoform X4

    5. XM_017319796.1XP_017175285.1  GON-4-like protein isoform X5

      Related
      ENSMUSP00000088461.5, ENSMUST00000090942.5
    6. XM_017319794.1XP_017175283.1  GON-4-like protein isoform X3

      Conserved Domains (2) summary
      cd12202
      Location:21622227
      CASP8AP2; Caspase 8-associated protein 2 myb-like domain
      pfam02671
      Location:16711716
      PAH; Paired amphipathic helix repeat
    7. XM_017319797.1XP_017175286.1  GON-4-like protein isoform X6

      Conserved Domains (2) summary
      cd12202
      Location:21542219
      CASP8AP2; Caspase 8-associated protein 2 myb-like domain
      pfam02671
      Location:16631708
      PAH; Paired amphipathic helix repeat
    8. XM_017319800.1XP_017175289.1  GON-4-like protein isoform X9

      Conserved Domains (2) summary
      cd12202
      Location:21532218
      CASP8AP2; Caspase 8-associated protein 2 myb-like domain
      pfam02671
      Location:16631708
      PAH; Paired amphipathic helix repeat
    9. XM_017319798.1XP_017175287.1  GON-4-like protein isoform X7

    10. XM_017319799.1XP_017175288.1  GON-4-like protein isoform X8

    11. XM_006502239.3XP_006502302.1  GON-4-like protein isoform X1

      See identical proteins and their annotated locations for XP_006502302.1

      Conserved Domains (2) summary
      cd12202
      Location:21632228
      CASP8AP2; Caspase 8-associated protein 2 myb-like domain
      pfam02671
      Location:16721717
      PAH; Paired amphipathic helix repeat
    12. XM_006502238.3XP_006502301.1  GON-4-like protein isoform X1

      See identical proteins and their annotated locations for XP_006502301.1

      Conserved Domains (2) summary
      cd12202
      Location:21632228
      CASP8AP2; Caspase 8-associated protein 2 myb-like domain
      pfam02671
      Location:16721717
      PAH; Paired amphipathic helix repeat
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