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    Zmym2 zinc finger, MYM-type 2 [ Mus musculus (house mouse) ]

    Gene ID: 76007, updated on 2-Oct-2018

    Summary

    Official Symbol
    Zmym2provided by MGI
    Official Full Name
    zinc finger, MYM-type 2provided by MGI
    Primary source
    MGI:MGI:1923257
    See related
    Ensembl:ENSMUSG00000021945
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    FIM; MYM; RAMP; SCLL; Zfp198; Znf198; 5830413P05Rik
    Summary
    This gene encodes a protein that contains nine MYM-type zinc finger motifs. Expression of this gene may mediate the inhibition of hematopoietic cell development during ontogeny, and the encoded protein may also play a role in transforming growth factor-beta signaling as a Smad binding protein. [provided by RefSeq, Feb 2011]
    Expression
    Broad expression in CNS E11.5 (RPKM 12.5), CNS E14 (RPKM 11.4) and 25 other tissues See more
    Orthologs

    Genomic context

    See Zmym2 in Genome Data Viewer
    Location:
    14; 14 C3
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (56886421..56962579)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (57506631..57579186)

    Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 48906 Neighboring gene cyclin I pseudogene Neighboring gene RIKEN cDNA B020004C17 gene Neighboring gene predicted gene, 36789

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Chemically induced (ENU) (1) 

    Pathways from BioSystems

    • PluriNetWork, organism-specific biosystem (from WikiPathways)
      PluriNetWork, organism-specific biosystemThe aim of the PluriNetWork is to give an overview of specific mechanisms associated with pluripotency in mouse. Each node represents a gene and its corresponding protein product. As stated, we inten...

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC51607

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    ubiquitin conjugating enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of cell morphogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    PML body ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    zinc finger MYM-type protein 2
    Names
    zinc finger protein 198

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001360643.1NP_001347572.1  zinc finger MYM-type protein 2 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC154303, AK135499, AK137720, AV142652, BE993957, BU055093, CA536924, CV561457
      Conserved Domains (2) summary
      pfam06467
      Location:461501
      zf-FCS; MYM-type Zinc finger with FCS sequence motif
      pfam12012
      Location:11911358
      DUF3504; Domain of unknown function (DUF3504)
    2. NM_029498.4NP_083774.2  zinc finger MYM-type protein 2 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC154303, AK135499, AK137720, AV142652, BE993957, CA536924, CJ110016, CV561457
      Consensus CDS
      CCDS49506.1
      UniProtKB/Swiss-Prot
      Q9CU65
      Related
      ENSMUSP00000022511.8, ENSMUST00000022511.9
      Conserved Domains (2) summary
      pfam06467
      Location:461501
      zf-FCS; MYM-type Zinc finger with FCS sequence motif
      pfam12012
      Location:11911358
      DUF3504; Domain of unknown function (DUF3504)
    3. NM_177627.3NP_808295.2  zinc finger MYM-type protein 2 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AC154303, AK135499, CJ110016

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

      Range
      56886421..56962579
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011245220.2XP_011243522.1  zinc finger MYM-type protein 2 isoform X1

      Conserved Domains (2) summary
      pfam06467
      Location:458501
      zf-FCS; MYM-type Zinc finger with FCS sequence motif
      pfam12012
      Location:12171384
      DUF3504; Domain of unknown function (DUF3504)
    2. XM_006519665.3XP_006519728.1  zinc finger MYM-type protein 2 isoform X2

      UniProtKB/Swiss-Prot
      Q9CU65
      Conserved Domains (2) summary
      pfam06467
      Location:461501
      zf-FCS; MYM-type Zinc finger with FCS sequence motif
      pfam12012
      Location:11911358
      DUF3504; Domain of unknown function (DUF3504)
    3. XM_011245221.2XP_011243523.1  zinc finger MYM-type protein 2 isoform X1

      Conserved Domains (2) summary
      pfam06467
      Location:458501
      zf-FCS; MYM-type Zinc finger with FCS sequence motif
      pfam12012
      Location:12171384
      DUF3504; Domain of unknown function (DUF3504)
    4. XM_017316221.1XP_017171710.1  zinc finger MYM-type protein 2 isoform X2

      UniProtKB/Swiss-Prot
      Q9CU65
      Conserved Domains (2) summary
      pfam06467
      Location:461501
      zf-FCS; MYM-type Zinc finger with FCS sequence motif
      pfam12012
      Location:11911358
      DUF3504; Domain of unknown function (DUF3504)
    5. XM_011245219.2XP_011243521.1  zinc finger MYM-type protein 2 isoform X1

      Conserved Domains (2) summary
      pfam06467
      Location:458501
      zf-FCS; MYM-type Zinc finger with FCS sequence motif
      pfam12012
      Location:12171384
      DUF3504; Domain of unknown function (DUF3504)
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