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    Slain2 SLAIN motif family, member 2 [ Mus musculus (house mouse) ]

    Gene ID: 75991, updated on 22-Aug-2021

    Summary

    Official Symbol
    Slain2provided by MGI
    Official Full Name
    SLAIN motif family, member 2provided by MGI
    Primary source
    MGI:MGI:1923241
    See related
    Ensembl:ENSMUSG00000036087
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI596370; 5033405K12Rik; 8030444K12Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 52.4), heart adult (RPKM 16.2) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Slain2 in Genome Data Viewer
    Location:
    5; 5 C3.2
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (73071705..73136184)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (72914362..72978841)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (73305556..73370067)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene TXK tyrosine kinase Neighboring gene tec protein tyrosine kinase Neighboring gene predicted gene, 54302 Neighboring gene predicted gene, 54289 Neighboring gene solute carrier family 10 (sodium/bile acid cotransporter family), member 4 Neighboring gene zygote arrest 1, pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • KIAA1458, MGC47019

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in cytoplasmic microtubule organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in cytoplasmic microtubule organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cytoplasmic microtubule organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in microtubule nucleation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in microtubule nucleation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of microtubule polymerization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in positive regulation of microtubule polymerization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of microtubule polymerization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in microtubule cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with microtubule plus-end IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    colocalizes_with microtubule plus-end ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    SLAIN motif-containing protein 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001113423.2NP_001106894.1  SLAIN motif-containing protein 2 isoform b

      See identical proteins and their annotated locations for NP_001106894.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region, compared to variant1. It encodes isoform b, which lacks an internal segment and is shorter, compared to isoform a.
      Source sequence(s)
      AK029260, BB618957, BC076573, BY423831, BY736933
      Consensus CDS
      CCDS51517.1
      UniProtKB/Swiss-Prot
      Q8CI08
      Related
      ENSMUSP00000116528.2, ENSMUST00000144843.8
      Conserved Domains (1) summary
      pfam15301
      Location:130581
      SLAIN; SLAIN motif-containing family
    2. NM_153567.3NP_705795.2  SLAIN motif-containing protein 2 isoform a

      See identical proteins and their annotated locations for NP_705795.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
      Source sequence(s)
      AK029260, AK039970, BB618957, BC076573, BY423831, BY736933, CF534366, CF728452, CK619668
      Consensus CDS
      CCDS19335.2
      UniProtKB/Swiss-Prot
      Q8CI08
      Related
      ENSMUSP00000115871.2, ENSMUST00000143829.5
      Conserved Domains (1) summary
      pfam15301
      Location:130607
      SLAIN; SLAIN motif-containing family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      73071705..73136184
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006504171.3XP_006504234.1  SLAIN motif-containing protein 2 isoform X1

      Conserved Domains (1) summary
      pfam15301
      Location:1466
      SLAIN; SLAIN motif-containing family
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