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    Vmp1 vacuole membrane protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 75909, updated on 23-Jun-2021

    Summary

    Official Symbol
    Vmp1provided by MGI
    Official Full Name
    vacuole membrane protein 1provided by MGI
    Primary source
    MGI:MGI:1923159
    See related
    Ensembl:ENSMUSG00000018171
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tan; ni-2; Tango5; Tmem49; mir-21a; AI787464; 3110098I04Rik; 4930579A11Rik
    Expression
    Ubiquitous expression in placenta adult (RPKM 30.4), bladder adult (RPKM 28.1) and 25 other tissues See more
    Orthologs
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    Genomic context

    See Vmp1 in Genome Data Viewer
    Location:
    11; 11 C
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (86474684..86574662, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (86583858..86683836, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (86397367..86497324, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene ring finger protein, transmembrane 1 Neighboring gene ribosomal protein S6 kinase, polypeptide 1 Neighboring gene tubulin, delta 1 Neighboring gene VISTA enhancer mm127 Neighboring gene microRNA 21a Neighboring gene predicted gene, 46289 Neighboring gene predicted gene, 51914 Neighboring gene predicted gene 11478 Neighboring gene peptidyl-tRNA hydrolase 2 Neighboring gene clathrin, heavy polypeptide (Hc) Neighboring gene predicted gene, 42085

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in Golgi organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in autophagosome assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in autophagosome membrane docking ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in autophagy IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in autophagy IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in autophagy ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cell junction assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cell-cell adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within embryo implantation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in lipoprotein transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in lipoprotein transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitochondrion-endoplasmic reticulum membrane tethering ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in organelle localization by membrane tethering ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of ATPase-coupled calcium transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in autophagosome membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in phagophore assembly site IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in vacuole IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    vacuole membrane protein 1
    Names
    NF-E2 induceble protein-2
    protein ni-2
    transmembrane protein 49

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001356531.3NP_001343460.1  vacuole membrane protein 1 isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2), as well as variants 1 and 3, encodes isoform a.
      Source sequence(s)
      AL592222, AL604063
      Consensus CDS
      CCDS25203.1
      Conserved Domains (1) summary
      cl00429
      Location:247298
      SNARE_assoc; SNARE associated Golgi protein
    2. NM_001379040.1NP_001365969.1  vacuole membrane protein 1 isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) represents the longest transcript and encodes the longer isoform (a). Variants 1-3 all encode the same isoform (a).
      Source sequence(s)
      AL592222, AL604063
      Conserved Domains (1) summary
      cl00429
      Location:247298
      SNARE_assoc; SNARE associated Golgi protein
    3. NM_001379041.1NP_001365970.1  vacuole membrane protein 1 isoform b

      Status: VALIDATED

      Source sequence(s)
      AL592222, AL604063
      Conserved Domains (1) summary
      cl00429
      Location:247298
      SNARE_assoc; SNARE associated Golgi protein
    4. NM_029478.6NP_083754.2  vacuole membrane protein 1 isoform a

      See identical proteins and their annotated locations for NP_083754.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1), as well as variants 2 and 3, encodes isoform a.
      Source sequence(s)
      AL592222, AL604063
      Consensus CDS
      CCDS25203.1
      UniProtKB/Swiss-Prot
      Q99KU0
      Related
      ENSMUSP00000018315.4, ENSMUST00000018315.10
      Conserved Domains (1) summary
      cl00429
      Location:247298
      SNARE_assoc; SNARE associated Golgi protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      86474684..86574662 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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