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    Dcp1a decapping mRNA 1A [ Mus musculus (house mouse) ]

    Gene ID: 75901, updated on 8-Jul-2021

    Summary

    Official Symbol
    Dcp1aprovided by MGI
    Official Full Name
    decapping mRNA 1Aprovided by MGI
    Primary source
    MGI:MGI:1923151
    See related
    Ensembl:ENSMUSG00000021962
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    SM; Mitc; SMIF; Mitc1; AU019772; D14Ertd817; D14Ertd817e; 1110066A22Rik; 4930568L04Rik
    Expression
    Ubiquitous expression in thymus adult (RPKM 10.4), limb E14.5 (RPKM 9.9) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Dcp1a in Genome Data Viewer
    Location:
    14 B; 14 18.75 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (30201443..30249013)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (30479486..30527056)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (31292751..31340242)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene calcium channel, voltage-dependent, L type, alpha 1D subunit Neighboring gene RIKEN cDNA 4831407H17 gene Neighboring gene microtubule-associated protein 1S pseudogene Neighboring gene predicted gene, 35566 Neighboring gene microRNA 3076 Neighboring gene transketolase Neighboring gene predicted gene, 52147 Neighboring gene protein kinase C, delta

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables enzyme activator activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables kinesin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables transcription factor binding ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in P-body IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in P-body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasmic ribonucleoprotein granule ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of transcription regulator complex ISA
    Inferred from Sequence Alignment
    more info
    PubMed 

    General protein information

    Preferred Names
    mRNA-decapping enzyme 1A
    Names
    DCP1 decapping enzyme homolog A
    MAD homolog 4 interacting transcription coactivator 1
    Smad4-interacting transcriptional co-activator
    decapping enzyme
    transcription factor SMIF

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_133761.3NP_598522.3  mRNA-decapping enzyme 1A

      See identical proteins and their annotated locations for NP_598522.3

      Status: VALIDATED

      Source sequence(s)
      AC119886, AK016254, CK392647, CO429593, DV651307
      Consensus CDS
      CCDS36848.1
      UniProtKB/Swiss-Prot
      Q91YD3
      Related
      ENSMUSP00000022535.8, ENSMUST00000022535.9
      Conserved Domains (2) summary
      cd09804
      Location:26146
      Dcp1; mRNA decapping enzyme 1 (Dcp1)
      pfam16741
      Location:559601
      mRNA_decap_C; mRNA-decapping enzyme C-terminus

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      30201443..30249013
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006519656.3XP_006519719.1  mRNA-decapping enzyme 1A isoform X2

      Conserved Domains (2) summary
      cd09804
      Location:26146
      Dcp1; mRNA decapping enzyme 1 (Dcp1)
      pfam16741
      Location:521563
      mRNA_decap_C; mRNA-decapping enzyme C-terminus
    2. XM_006519655.5XP_006519718.1  mRNA-decapping enzyme 1A isoform X1

      Conserved Domains (3) summary
      cd09804
      Location:26146
      Dcp1; mRNA decapping enzyme 1 (Dcp1)
      pfam16014
      Location:308456
      SAP130_C; Histone deacetylase complex subunit SAP130 C-terminus
      pfam16741
      Location:537579
      mRNA_decap_C; mRNA-decapping enzyme C-terminus
    3. XM_036158891.1XP_036014784.1  mRNA-decapping enzyme 1A isoform X3

      Conserved Domains (3) summary
      cd09804
      Location:26146
      Dcp1; mRNA decapping enzyme 1 (Dcp1)
      PHA03247
      Location:293508
      PHA03247; large tegument protein UL36; Provisional
      pfam16741
      Location:499541
      mRNA_decap_C; mRNA-decapping enzyme C-terminus
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