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    Ckap5 cytoskeleton associated protein 5 [ Mus musculus (house mouse) ]

    Gene ID: 75786, updated on 9-Sep-2018

    Summary

    Official Symbol
    Ckap5provided by MGI
    Official Full Name
    cytoskeleton associated protein 5provided by MGI
    Primary source
    MGI:MGI:1923036
    See related
    Ensembl:ENSMUSG00000040549 Vega:OTTMUSG00000014251
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    T25636; mKIAA0097; 3110043H24Rik; 4930432B04Rik; D730027C18Rik
    Expression
    Broad expression in CNS E11.5 (RPKM 33.2), CNS E14 (RPKM 22.3) and 21 other tissues See more
    Orthologs

    Genomic context

    See Ckap5 in Genome Data Viewer
    Location:
    2; 2 E1
    Exon count:
    46
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (91526747..91620679)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (91386479..91460822)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene low density lipoprotein receptor-related protein 4 Neighboring gene predicted gene 13770 Neighboring gene small nucleolar RNA, C/D box 67 Neighboring gene coagulation factor II Neighboring gene cytochrome c oxidase subunit 7B, mitochondrial pseudogene Neighboring gene zinc finger protein 408 Neighboring gene Rho GTPase activating protein 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    microtubule binding ISO
    Inferred from Sequence Orthology
    more info
     
    microtubule plus-end binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ribonucleoprotein complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cell division IEA
    Inferred from Electronic Annotation
    more info
     
    centrosome cycle ISO
    Inferred from Sequence Orthology
    more info
     
    centrosome duplication IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    establishment or maintenance of microtubule cytoskeleton polarity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    establishment or maintenance of microtubule cytoskeleton polarity ISO
    Inferred from Sequence Orthology
    more info
     
    microtubule polymerization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    spindle organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    spindle organization ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    chromosome, centromeric region IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    colocalizes_with gamma-tubulin complex ISO
    Inferred from Sequence Orthology
    more info
     
    kinetochore IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    kinetochore ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with microtubule plus-end IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    colocalizes_with microtubule plus-end ISO
    Inferred from Sequence Orthology
    more info
     
    nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    spindle pole IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    spindle pole ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    cytoskeleton-associated protein 5
    Names
    ckap5

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001165989.2NP_001159461.1  cytoskeleton-associated protein 5 isoform 1

      See identical proteins and their annotated locations for NP_001159461.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AL691489
      Consensus CDS
      CCDS50640.1
      UniProtKB/TrEMBL
      K3W4R5
      Related
      ENSMUSP00000097303.4, ENSMUST00000099716.10
      Conserved Domains (1) summary
      pfam12348
      Location:8561048
      CLASP_N; CLASP N terminal
    2. NM_029437.2NP_083713.2  cytoskeleton-associated protein 5 isoform 2

      See identical proteins and their annotated locations for NP_083713.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice junction at the 5' end of an exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
      Source sequence(s)
      BC089032, BC096422
      Consensus CDS
      CCDS16433.1
      UniProtKB/Swiss-Prot
      A2AGT5
      UniProtKB/TrEMBL
      A0A0R4J0K2
      Related
      ENSMUSP00000046263.9, ENSMUST00000046769.15
      Conserved Domains (1) summary
      pfam12348
      Location:8561048
      CLASP_N; CLASP N terminal

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

      Range
      91526747..91620679
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006500342.1XP_006500405.1  cytoskeleton-associated protein 5 isoform X1

      See identical proteins and their annotated locations for XP_006500405.1

      Conserved Domains (1) summary
      pfam12348
      Location:8561048
      CLASP_N; CLASP N terminal
    2. XM_006500344.3XP_006500407.1  cytoskeleton-associated protein 5 isoform X2

      UniProtKB/TrEMBL
      K3W4R5
      Related
      ENSMUSP00000106970.3, OTTMUSP00000015053, ENSMUST00000111338.9, OTTMUST00000033540
      Conserved Domains (1) summary
      pfam12348
      Location:8561048
      CLASP_N; CLASP N terminal
    3. XM_006500343.2XP_006500406.1  cytoskeleton-associated protein 5 isoform X1

      See identical proteins and their annotated locations for XP_006500406.1

      Conserved Domains (1) summary
      pfam12348
      Location:8561048
      CLASP_N; CLASP N terminal
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