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    Rab11fip1 RAB11 family interacting protein 1 (class I) [ Mus musculus (house mouse) ]

    Gene ID: 75767, updated on 5-Aug-2018

    Summary

    Official Symbol
    Rab11fip1provided by MGI
    Official Full Name
    RAB11 family interacting protein 1 (class I)provided by MGI
    Primary source
    MGI:MGI:1923017
    See related
    Ensembl:ENSMUSG00000031488 Vega:OTTMUSG00000060990
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rcp; 2010200K21Rik; 4833414G05Rik
    Expression
    Broad expression in lung adult (RPKM 12.6), colon adult (RPKM 11.6) and 20 other tissues See more
    Orthologs

    Genomic context

    See Rab11fip1 in Genome Data Viewer
    Location:
    8; 8 A2
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (27138773..27174646, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (28249245..28285118, complement)

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 39151 Neighboring gene adhesion G protein-coupled receptor A2 Neighboring gene BRF2, RNA polymerase III transcription initiation factor 50kDa subunit Neighboring gene RIKEN cDNA 4933416M07 gene Neighboring gene glutamic-oxaloacetic transaminase 1-like 1 Neighboring gene adrenergic receptor, beta 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    • Endocytosis, organism-specific biosystem (from KEGG)
      Endocytosis, organism-specific biosystemEndocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins en...
    • Endocytosis, conserved biosystem (from KEGG)
      Endocytosis, conserved biosystemEndocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins en...

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Clone Names

    • MGC159103

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    Rab GTPase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    negative regulation of adiponectin secretion ISO
    Inferred from Sequence Orthology
    more info
     
    protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    regulated exocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    endosome IEA
    Inferred from Electronic Annotation
    more info
     
    intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    rab11 family-interacting protein 1
    Names
    Rab coupling protein
    rab-coupling protein
    rab11-FIP1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080813.2NP_001074282.1  rab11 family-interacting protein 1 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC119917
      Consensus CDS
      CCDS40311.1
      UniProtKB/TrEMBL
      E9Q8L9
      Related
      ENSMUSP00000058042.6, OTTMUSP00000077406, ENSMUST00000054212.6, OTTMUST00000149063
      Conserved Domains (2) summary
      cd08682
      Location:20149
      C2_Rab11-FIP_classI; C2 domain found in Rab11-family interacting proteins (FIP) class I
      pfam09457
      Location:11091156
      RBD-FIP; FIP domain
    2. NM_029423.2NP_083699.2  rab11 family-interacting protein 1 isoform 2

      See identical proteins and their annotated locations for NP_083699.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon in the coding region, compared to variant 1. The resulting isoform (2) lacks an internal segment, compared to isoform 1.
      Source sequence(s)
      AC119917, BB619642, BC132094
      Consensus CDS
      CCDS52534.1
      UniProtKB/Swiss-Prot
      Q9D620
      Related
      ENSMUSP00000033878.6, OTTMUSP00000077407, ENSMUST00000033878.13, OTTMUST00000149064
      Conserved Domains (2) summary
      cd08682
      Location:20149
      C2_Rab11-FIP_classI; C2 domain found in Rab11-family interacting proteins (FIP) class I
      pfam09457
      Location:588635
      RBD-FIP; FIP domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

      Range
      27138773..27174646 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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