Format

Send to:

Choose Destination
    • Showing Current items.

    Shld2 shieldin complex subunit 2 [ Mus musculus (house mouse) ]

    Gene ID: 75698, updated on 23-Jun-2021

    Summary

    Official Symbol
    Shld2provided by MGI
    Official Full Name
    shieldin complex subunit 2provided by MGI
    Primary source
    MGI:MGI:1922948
    See related
    Ensembl:ENSMUSG00000041471
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fam3; Fam35a; 3110001K24Rik
    Expression
    Ubiquitous expression in liver E18 (RPKM 3.2), liver adult (RPKM 2.5) and 26 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Shld2 in Genome Data Viewer
    Location:
    14; 14 B
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (33958905..34032528, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (34236948..34310651, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (35050219..35123689, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene VISTA enhancer mm340 Neighboring gene G protein regulated inducer of neurite outgrowth 2 Neighboring gene synaptotagmin XV Neighboring gene zinc finger, DHHC domain containing 17 pseudogene Neighboring gene glutamate dehydrogenase 1 Neighboring gene B-cell CLL/lymphoma 7C pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in chromosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in site of double-strand break IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in site of double-strand break ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    shieldin complex subunit 2
    Names
    RINN1-REV7-interacting novel NHEJ regulator 2
    family with sequence similarity 35, member A
    protein FAM35A

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001360074.1NP_001347003.1  shieldin complex subunit 2

      Status: VALIDATED

      Source sequence(s)
      AC154738, AK149442, BE630700, BE648821, BE848901, BF467362, BQ829235, BU756157
      Consensus CDS
      CCDS36874.1
      Conserved Domains (1) summary
      pfam15793
      Location:695866
      FAM35_C; Protein family FAM35, C-terminal
    2. NM_029389.3NP_083665.2  shieldin complex subunit 2

      See identical proteins and their annotated locations for NP_083665.2

      Status: VALIDATED

      Source sequence(s)
      AI451789, AK149442, BF467362, BU756157, CD547520
      Consensus CDS
      CCDS36874.1
      UniProtKB/Swiss-Prot
      Q3UEN2
      Related
      ENSMUSP00000107548.2, ENSMUST00000111917.3
      Conserved Domains (1) summary
      pfam15793
      Location:695866
      FAM35_C; Protein family FAM35, C-terminal

    RNA

    1. NR_153399.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC154738, AC160930, AK149442, BE630700, BE848901, BF467362, BQ829235, BU756157

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      33958905..34032528 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006519652.5XP_006519715.1  shieldin complex subunit 2 isoform X4

      See identical proteins and their annotated locations for XP_006519715.1

      Conserved Domains (1) summary
      pfam15793
      Location:143314
      FAM35_C; Protein family FAM35, C-terminal
    2. XM_017316219.3XP_017171708.1  shieldin complex subunit 2 isoform X4

      Conserved Domains (1) summary
      pfam15793
      Location:143314
      FAM35_C; Protein family FAM35, C-terminal
    3. XM_011245218.4XP_011243520.1  shieldin complex subunit 2 isoform X2

      Conserved Domains (1) summary
      pfam15793
      Location:659830
      FAM35_C; Protein family FAM35, C-terminal
    4. XM_006519650.5XP_006519713.1  shieldin complex subunit 2 isoform X3

      Conserved Domains (1) summary
      pfam15793
      Location:178349
      FAM35_C; Protein family FAM35, C-terminal
    5. XM_006519651.4XP_006519714.1  shieldin complex subunit 2 isoform X4

      See identical proteins and their annotated locations for XP_006519714.1

      Conserved Domains (1) summary
      pfam15793
      Location:143314
      FAM35_C; Protein family FAM35, C-terminal
    6. XM_011245216.4XP_011243518.1  shieldin complex subunit 2 isoform X1

      See identical proteins and their annotated locations for XP_011243518.1

      UniProtKB/Swiss-Prot
      Q3UEN2
      Conserved Domains (1) summary
      pfam15793
      Location:695866
      FAM35_C; Protein family FAM35, C-terminal
    7. XM_006519646.5XP_006519709.1  shieldin complex subunit 2 isoform X1

      See identical proteins and their annotated locations for XP_006519709.1

      UniProtKB/Swiss-Prot
      Q3UEN2
      Conserved Domains (1) summary
      pfam15793
      Location:695866
      FAM35_C; Protein family FAM35, C-terminal
    8. XM_006519648.5XP_006519711.1  shieldin complex subunit 2 isoform X1

      See identical proteins and their annotated locations for XP_006519711.1

      UniProtKB/Swiss-Prot
      Q3UEN2
      Conserved Domains (1) summary
      pfam15793
      Location:695866
      FAM35_C; Protein family FAM35, C-terminal
    9. XM_006519645.5XP_006519708.1  shieldin complex subunit 2 isoform X1

      See identical proteins and their annotated locations for XP_006519708.1

      UniProtKB/Swiss-Prot
      Q3UEN2
      Conserved Domains (1) summary
      pfam15793
      Location:695866
      FAM35_C; Protein family FAM35, C-terminal

    RNA

    1. XR_001781163.3 RNA Sequence

    Support Center