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    Nr2c2ap nuclear receptor 2C2-associated protein [ Mus musculus (house mouse) ]

    Gene ID: 75692, updated on 31-Jan-2019

    Summary

    Official Symbol
    Nr2c2approvided by MGI
    Official Full Name
    nuclear receptor 2C2-associated proteinprovided by MGI
    Primary source
    MGI:MGI:1922942
    See related
    Ensembl:ENSMUSG00000071078
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2310073E15Rik
    Expression
    Ubiquitous expression in large intestine adult (RPKM 15.0), thymus adult (RPKM 13.1) and 28 other tissues See more
    Orthologs

    Genomic context

    See Nr2c2ap in Genome Data Viewer
    Location:
    8; 8 B3.3
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (70131327..70133752)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (72655232..72657647)

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene hyaluronan and proteoglycan link protein 4 Neighboring gene neurocan Neighboring gene microRNA 7066 Neighboring gene regulatory factor X-associated ankyrin-containing protein Neighboring gene predicted gene, 45929 Neighboring gene BLOC-1 related complex subunit 8 Neighboring gene myocyte enhancer factor 2B

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Clone Names

    • MGC103332

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    nuclear receptor 2C2-associated protein
    Names
    TR4 orphan receptor-associated 16 kDa protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025586.2NP_001020757.1  nuclear receptor 2C2-associated protein isoform 1

      See identical proteins and their annotated locations for NP_001020757.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest protein (isoform 1).
      Source sequence(s)
      AA111465, AK160346, BY100716
      Consensus CDS
      CCDS40366.1
      UniProtKB/Swiss-Prot
      Q3TV70
      Related
      ENSMUSP00000092907.5, ENSMUST00000095273.6
      Conserved Domains (1) summary
      cl02148
      Location:1291
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
    2. NM_001025587.2NP_001020758.1  nuclear receptor 2C2-associated protein isoform 2

      See identical proteins and their annotated locations for NP_001020758.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This encodes a protein (isoform 2) that is shorter than isoform 1.
      Source sequence(s)
      AA111465, AK010864, AK160346, BY100716
      UniProtKB/Swiss-Prot
      Q3TV70
      UniProtKB/TrEMBL
      Q569V8
      Conserved Domains (1) summary
      cl02148
      Location:12102
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination

    RNA

    1. NR_104434.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an internal exon, compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
      Source sequence(s)
      AA111465, AK010864, BY100716
      Related
      ENSMUST00000211898.1

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

      Range
      70131327..70133752
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006509777.2XP_006509840.1  nuclear receptor 2C2-associated protein isoform X1

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001025588.1: Suppressed sequence

      Description
      NM_001025588.1: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.
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