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    Metap1 methionyl aminopeptidase 1 [ Mus musculus (house mouse) ]

    Gene ID: 75624, updated on 23-Jun-2021

    Summary

    Official Symbol
    Metap1provided by MGI
    Official Full Name
    methionyl aminopeptidase 1provided by MGI
    Primary source
    MGI:MGI:1922874
    See related
    Ensembl:ENSMUSG00000005813
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AW047992; mKIAA0094; 1700029C17Rik
    Expression
    Ubiquitous expression in placenta adult (RPKM 27.6), CNS E11.5 (RPKM 21.6) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Metap1 in Genome Data Viewer
    Location:
    3; 3 G3
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (138164721..138195143, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (138458960..138489382, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (138121924..138152346, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene alcohol dehydrogenase 4 (class II), pi polypeptide Neighboring gene alcohol dehydrogenase 5 (class III), chi polypeptide Neighboring gene predicted gene, 32553 Neighboring gene microRNA 1956 Neighboring gene eukaryotic translation initiation factor 4E Neighboring gene predicted gene, 29762

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • KIAA0094

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables aminopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metalloaminopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables peptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    methionine aminopeptidase 1
    Names
    MAP 1
    Putative methionine aminopeptidase 1 (MetAP 1) (Peptidase M 1)
    metAP 1
    peptidase M 1
    NP_780433.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175224.4NP_780433.1  methionine aminopeptidase 1

      See identical proteins and their annotated locations for NP_780433.1

      Status: PROVISIONAL

      Source sequence(s)
      AC079845
      Consensus CDS
      CCDS17869.1
      UniProtKB/Swiss-Prot
      Q8BP48
      UniProtKB/TrEMBL
      Q4VAA9
      Related
      ENSMUSP00000029804.9, ENSMUST00000029804.13
      Conserved Domains (1) summary
      cl00279
      Location:14382
      APP_MetAP; A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      138164721..138195143 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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