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    Chmp4b charged multivesicular body protein 4B [ Mus musculus (house mouse) ]

    Gene ID: 75608, updated on 31-Jan-2019

    Summary

    Official Symbol
    Chmp4bprovided by MGI
    Official Full Name
    charged multivesicular body protein 4Bprovided by MGI
    Primary source
    MGI:MGI:1922858
    See related
    Ensembl:ENSMUSG00000038467
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C76846; Snf7-2; 2010012F05Rik
    Expression
    Ubiquitous expression in placenta adult (RPKM 92.6), bladder adult (RPKM 83.6) and 28 other tissues See more
    Orthologs

    Genomic context

    See Chmp4b in Genome Data Viewer
    Location:
    2; 2 H1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (154657026..154694783)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (154482762..154520519)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene peroxisomal membrane protein 4 Neighboring gene zinc finger protein 341 Neighboring gene predicted gene 14198 Neighboring gene RIKEN cDNA 9030607L20 gene Neighboring gene ribisomal protein L5, pseudogene 2 Neighboring gene predicted gene 14216

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    autophagy ISO
    Inferred from Sequence Orthology
    more info
     
    exit from mitosis ISO
    Inferred from Sequence Orthology
    more info
     
    maintenance of lens transparency ISO
    Inferred from Sequence Orthology
    more info
     
    membrane fission ISO
    Inferred from Sequence Orthology
    more info
     
    midbody abscission ISO
    Inferred from Sequence Orthology
    more info
     
    mitotic cytokinesis ISO
    Inferred from Sequence Orthology
    more info
     
    mitotic metaphase plate congression ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of autophagosome assembly ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of cell death ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of neuron death ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear envelope reassembly ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus organization ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of viral release from host cell ISO
    Inferred from Sequence Orthology
    more info
     
    posttranslational protein targeting to endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    protein homooligomerization ISO
    Inferred from Sequence Orthology
    more info
     
    protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of autophagy IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of centrosome duplication ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of mitotic spindle assembly ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of postsynapse organization ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of viral process ISO
    Inferred from Sequence Orthology
    more info
     
    ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway ISO
    Inferred from Sequence Orthology
    more info
     
    vacuolar transport IEA
    Inferred from Electronic Annotation
    more info
     
    viral budding ISO
    Inferred from Sequence Orthology
    more info
     
    viral budding via host ESCRT complex ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    ESCRT III complex ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasmic side of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    endosome ISO
    Inferred from Sequence Orthology
    more info
     
    glutamatergic synapse ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    membrane coat ISO
    Inferred from Sequence Orthology
    more info
     
    midbody ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear envelope ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    postsynaptic density ISO
    Inferred from Sequence Orthology
    more info
     
    vesicle ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    charged multivesicular body protein 4b
    Names
    chromatin modifying protein 4B
    chromatin-modifying protein 4b

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029362.3NP_083638.1  charged multivesicular body protein 4b

      See identical proteins and their annotated locations for NP_083638.1

      Status: VALIDATED

      Source sequence(s)
      AK159193, CF379912, CK628208
      Consensus CDS
      CCDS16938.1
      UniProtKB/Swiss-Prot
      Q9D8B3
      Related
      ENSMUSP00000036206.9, ENSMUST00000044277.9
      Conserved Domains (1) summary
      pfam03357
      Location:24198
      Snf7; Snf7

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

      Range
      154657026..154694783
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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