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    Ndufaf2 NADH:ubiquinone oxidoreductase complex assembly factor 2 [ Mus musculus (house mouse) ]

    Gene ID: 75597, updated on 23-May-2018

    Summary

    Official Symbol
    Ndufaf2provided by MGI
    Official Full Name
    NADH:ubiquinone oxidoreductase complex assembly factor 2provided by MGI
    Primary source
    MGI:MGI:1922847
    See related
    Ensembl:ENSMUSG00000068184
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C86051; mimitin; Ndufa12l; 1810058I14Rik
    Expression
    Broad expression in testis adult (RPKM 15.4), CNS E11.5 (RPKM 15.4) and 22 other tissues See more
    Orthologs

    Genomic context

    See Ndufaf2 in Genome Data Viewer
    Location:
    13; 13 D2.1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 13 NC_000079.6 (108052589..108158655, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (108842783..108948819, complement)

    Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 41055 Neighboring gene small integral membrane protein 15 Neighboring gene predicted gene, 32268 Neighboring gene excision repaiross-complementing rodent repair deficiency, complementation group 8 Neighboring gene ELOVL family member 7, elongation of long chain fatty acids (yeast) Neighboring gene predicted gene, 32376

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    NADH dehydrogenase (ubiquinone) activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    electron transfer activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cellular respiration IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cellular respiration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of insulin secretion involved in cellular response to glucose stimulus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    reactive oxygen species metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    respiratory electron transport chain IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2; mimitin, mitochondrial
    Names
    MMTN
    Myc-induced mitochondria protein
    NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 2
    NDUFA12-like protein
    myc-induced mitochondrial protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001127346.1NP_001120818.1  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 isoform 1

      See identical proteins and their annotated locations for NP_001120818.1

      Status: VALIDATED

      Source sequence(s)
      AW123826, BC116975, BY251841
      Consensus CDS
      CCDS49357.1
      UniProtKB/Swiss-Prot
      Q59J78
      Related
      ENSMUSP00000130532.1, ENSMUST00000163558.2
      Conserved Domains (1) summary
      pfam05071
      Location:2394
      NDUFA12; NADH ubiquinone oxidoreductase subunit NDUFA12
    2. NM_001360140.1NP_001347069.1  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC103379, CT025566
      Conserved Domains (1) summary
      cl01534
      Location:2384
      NDUFA12; NADH ubiquinone oxidoreductase subunit NDUFA12

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000079.6 Reference GRCm38.p4 C57BL/6J

      Range
      108052589..108158655 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006517779.2XP_006517842.1  mimitin, mitochondrial isoform X1

      Conserved Domains (1) summary
      cl01534
      Location:2384
      NDUFA12; NADH ubiquinone oxidoreductase subunit NDUFA12
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