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    Sgf29 SAGA complex associated factor 29 [ Mus musculus (house mouse) ]

    Gene ID: 75565, updated on 26-Sep-2022

    Summary

    Official Symbol
    Sgf29provided by MGI
    Official Full Name
    SAGA complex associated factor 29provided by MGI
    Primary source
    MGI:MGI:1922815
    See related
    Ensembl:ENSMUSG00000030714 AllianceGenome:MGI:1922815
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ccdc101; 1700023O11Rik; 9530025I05Rik
    Summary
    Predicted to enable enzyme binding activity; methylated histone binding activity; and protein N-terminus binding activity. Predicted to be involved in histone H3 acetylation. Predicted to act upstream of or within chromatin organization. Part of ATAC complex. Is expressed in genital tubercle; limb; and limb mesenchyme. Human ortholog(s) of this gene implicated in diabetic retinopathy. Orthologous to human SGF29 (SAGA complex associated factor 29). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in testis adult (RPKM 127.2), colon adult (RPKM 18.3) and 23 other tissues See more
    Orthologs
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    Genomic context

    See Sgf29 in Genome Data Viewer
    Location:
    7; 7 F3
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (126247558..126271951)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (126648386..126672779)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 39086 Neighboring gene predicted gene, 39087 Neighboring gene nuclear protein transcription regulator 1 Neighboring gene sulfotransferase family 1A, phenol-preferring, member 1 Neighboring gene sulfotransferase family 1A, phenol-preferring, member 1 pseudogene Neighboring gene SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables enzyme activator activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables methylated histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables methylated histone binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables methylation-dependent protein binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables molecular function inhibitor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein N-terminus binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within chromatin organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in histone H3 acetylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in histone H3 acetylation IC
    Inferred by Curator
    more info
    PubMed 
    involved_in histone H3 acetylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in histone H3-K14 acetylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in histone acetylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in monoubiquitinated histone H2A deubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in monoubiquitinated histone deubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of DNA-templated transcription IC
    Inferred by Curator
    more info
    PubMed 
    involved_in regulation of DNA repair IC
    Inferred by Curator
    more info
    PubMed 
    involved_in regulation of DNA repair IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of RNA splicing IC
    Inferred by Curator
    more info
    PubMed 
    involved_in regulation of cell cycle IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of cell division IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in regulation of cell division ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of embryonic development IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in regulation of histone deacetylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of tubulin deacetylation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of ATAC complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of ATAC complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of SAGA complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of SAGA complex IC
    Inferred by Curator
    more info
    PubMed 
    part_of SAGA-type complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitotic spindle IC
    Inferred by Curator
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    SAGA-associated factor 29
    Names
    SAGA-associated factor 29 homolog
    coiled-coil domain containing 101
    coiled-coil domain-containing protein 101

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029339.3NP_083615.3  SAGA-associated factor 29

      See identical proteins and their annotated locations for NP_083615.3

      Status: VALIDATED

      Source sequence(s)
      AK006287, AK139102, BE685896
      Consensus CDS
      CCDS21837.1
      UniProtKB/Swiss-Prot
      Q8R0I6, Q9DA08
      UniProtKB/TrEMBL
      A0A6P5Q2P2, A0A8C6MWM9
      Related
      ENSMUSP00000032956.9, ENSMUST00000032956.10
      Conserved Domains (1) summary
      pfam07039
      Location:158288
      DUF1325; SGF29 tudor-like domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      126247558..126271951
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017312365.2XP_017167854.1  SAGA-associated factor 29 isoform X1

      UniProtKB/Swiss-Prot
      Q8R0I6, Q9DA08
      UniProtKB/TrEMBL
      A0A6P5Q2P2, A0A8C6MWM9
      Conserved Domains (1) summary
      pfam07039
      Location:158288
      DUF1325; SGF29 tudor-like domain