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    Mphosph8 M-phase phosphoprotein 8 [ Mus musculus (house mouse) ]

    Gene ID: 75339, updated on 2-Oct-2018

    Summary

    Official Symbol
    Mphosph8provided by MGI
    Official Full Name
    M-phase phosphoprotein 8provided by MGI
    Primary source
    MGI:MGI:1922589
    See related
    Ensembl:ENSMUSG00000079184 Vega:OTTMUSG00000017272
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AU040635; 1500035L22Rik; 4930548G07Rik
    Expression
    Broad expression in CNS E11.5 (RPKM 15.4), CNS E14 (RPKM 8.2) and 21 other tissues See more
    Orthologs

    Genomic context

    See Mphosph8 in Genome Data Viewer
    Location:
    14; 14 C3
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (56668234..56697430)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (57287085..57316267)

    Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene poly (ADP-ribose) polymerase family, member 4 Neighboring gene predicted gene 16573 Neighboring gene transcription factor BTF3 pseudogene Neighboring gene predicted gene, 16973 Neighboring gene paraspeckle protein 1 Neighboring gene ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    methylated histone binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    negative regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of DNA methylation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear heterochromatin ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear nucleosome ISO
    Inferred from Sequence Orthology
    more info
     
    nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    M-phase phosphoprotein 8
    NP_076262.2
    XP_006519703.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001360072.1NP_001347001.1  M-phase phosphoprotein 8 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC154731, AK158773, BU757804, BY111264
      Conserved Domains (4) summary
      smart00298
      Location:58109
      CHROMO; Chromatin organization modifier domain
      cd00204
      Location:605729
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:613641
      ANK; ANK repeat [structural motif]
      cl26511
      Location:97482
      Neuromodulin_N; Gap junction protein N-terminal region
    2. NM_023773.2NP_076262.2  M-phase phosphoprotein 8 isoform 1

      See identical proteins and their annotated locations for NP_076262.2

      Status: VALIDATED

      Source sequence(s)
      AK158773, BU757804, BY111264
      Consensus CDS
      CCDS49504.1
      UniProtKB/Swiss-Prot
      Q3TYA6
      Related
      ENSMUSP00000112170.1, OTTMUSP00000018806, ENSMUST00000116468.1, OTTMUST00000041821
      Conserved Domains (4) summary
      smart00298
      Location:58109
      CHROMO; Chromatin organization modifier domain
      cd00204
      Location:593717
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:604693
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:601629
      ANK; ANK repeat [structural motif]

    RNA

    1. NR_153396.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      BC145164, BU757804, BY111264

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

      Range
      56668234..56697430
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006519640.3XP_006519703.1  M-phase phosphoprotein 8 isoform X1

      Conserved Domains (4) summary
      smart00298
      Location:58109
      CHROMO; Chromatin organization modifier domain
      cd00204
      Location:605729
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:613641
      ANK; ANK repeat [structural motif]
      cl26511
      Location:97482
      Neuromodulin_N; Gap junction protein N-terminal region

    RNA

    1. XR_383217.3 RNA Sequence

    2. XR_383218.3 RNA Sequence

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