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    Rnf121 ring finger protein 121 [ Mus musculus (house mouse) ]

    Gene ID: 75212, updated on 23-Jun-2021

    Summary

    Official Symbol
    Rnf121provided by MGI
    Official Full Name
    ring finger protein 121provided by MGI
    Primary source
    MGI:MGI:1922462
    See related
    Ensembl:ENSMUSG00000070426
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4930544L10Rik
    Expression
    Ubiquitous expression in placenta adult (RPKM 13.4), large intestine adult (RPKM 13.2) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Rnf121 in Genome Data Viewer
    Location:
    7; 7 E2
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (101668344..101721712, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (102019137..102072437, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (109168386..109213646, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene nuclear mitotic apparatus protein 1 Neighboring gene MYST histone acetyltransferase 1 pseudogene Neighboring gene predicted gene, 39061 Neighboring gene interleukin 18 binding protein Neighboring gene Xndc1-transient receptor potential cation channel, subfamily C, member 2 readthrough Neighboring gene Xrcc1 N-terminal domain containing 1 Neighboring gene transient receptor potential cation channel, subfamily C, member 2 Neighboring gene ADP-ribosyltransferase 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (3) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in ubiquitin-dependent ERAD pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001360748.1NP_001347677.1  RING finger protein 121 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC150275, AC167240, BE946466
      Conserved Domains (1) summary
      cd16475
      Location:70124
      RING-H2_RNF121_like; RING finger, H2 subclass, found in RING finger proteins RNF121, RNF175 and similar proteins
    2. NM_029211.3NP_083487.2  RING finger protein 121 isoform 1

      See identical proteins and their annotated locations for NP_083487.2

      Status: VALIDATED

      Source sequence(s)
      AC167240, AK159260, BE946466, BY316785
      Consensus CDS
      CCDS21523.1
      UniProtKB/Swiss-Prot
      Q8R1Z9
      Related
      ENSMUSP00000094396.6, ENSMUST00000096639.12
      Conserved Domains (1) summary
      cd16475
      Location:224278
      RING-H2_RNF121_like; RING finger, H2 subclass, found in RING finger proteins RNF121, RNF175 and similar proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      101668344..101721712 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006508275.4XP_006508338.1  RING finger protein 121 isoform X1

      See identical proteins and their annotated locations for XP_006508338.1

      UniProtKB/Swiss-Prot
      Q8R1Z9
      Conserved Domains (2) summary
      cd16475
      Location:212266
      RING-H2_RNF121_like; RING finger, H2 subclass, found in RING finger proteins RNF121, RNF175 and similar proteins
      cl28910
      Location:44200
      MFS; Major Facilitator Superfamily
    2. XM_030243047.2XP_030098907.1  RING finger protein 121 isoform X2

      Related
      ENSMUSP00000086453.5, ENSMUST00000089052.11
      Conserved Domains (1) summary
      cd16475
      Location:201255
      RING-H2_RNF121_like; RING finger, H2 subclass, found in RING finger proteins RNF121, RNF175 and similar proteins
    3. XM_030243048.2XP_030098908.1  RING finger protein 121 isoform X3

      Conserved Domains (1) summary
      cd16475
      Location:70124
      RING-H2_RNF121_like; RING finger, H2 subclass, found in RING finger proteins RNF121, RNF175 and similar proteins
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