Rasl2-9 RAS-like, family 2, locus 9 [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Rasl2-9provided by RGD
Full Name: RAS-like, family 2, locus 9provided by RGD
Primary source: RGD:2314256
See related: Ensembl:ENSRNOG00000032913 AllianceGenome:RGD:2314256
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable GTPase activity. Predicted to be involved in protein import into nucleus and ribosomal subunit export from nucleus. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human RAN (RAN, member RAS oncogene family). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

Location:: 1q12

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (77749728..77750905)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (68720879..68734930)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (72272032..72273210)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in protein import into nucleus	IBA Inferred from Biological aspect of Ancestor more info
involved_in ribosomal subunit export from nucleus	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: GTP-binding nuclear protein Ran, testis-specific isoform

Names: GTP-ase Ran

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001166675.1 → NP_001160147.1 GTP-binding nuclear protein Ran, testis-specific isoform

See identical proteins and their annotated locations for NP_001160147.1

Status: PROVISIONAL

Source sequence(s)

CH474075

UniProtKB/Swiss-Prot

Q8K586

UniProtKB/TrEMBL

A6KNS1

Related

ENSRNOP00000039019.2, ENSRNOT00000050233.5

Conserved Domains (1) summary

smart00176
Location:16 → 215

RAN; Ran (Ras-related nuclear proteins) /TC4 subfamily of small GTPases