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    Usp38 ubiquitin specific peptidase 38 [ Mus musculus (house mouse) ]

    Gene ID: 74841, updated on 23-Jun-2021

    Summary

    Official Symbol
    Usp38provided by MGI
    Official Full Name
    ubiquitin specific peptidase 38provided by MGI
    Primary source
    MGI:MGI:1922091
    See related
    Ensembl:ENSMUSG00000038250
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AA536967; AU044701; AW544820; mKIAA1891; 4631402N15Rik; 4833420O05Rik
    Expression
    Ubiquitous expression in placenta adult (RPKM 6.0), thymus adult (RPKM 5.7) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Usp38 in Genome Data Viewer
    Location:
    8 C2; 8 38.68 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (81707353..81741631, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (80980724..81015013, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (83504632..83538805, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene predicted gene, 31223 Neighboring gene predicted gene 9725 Neighboring gene coenzyme Q10 homolog B pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables cysteine-type endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables cysteine-type peptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables peptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables thiol-dependent deubiquitinase IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables thiol-dependent deubiquitinase ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in protein deubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in protein deubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    ubiquitin carboxyl-terminal hydrolase 38
    Names
    deubiquitinating enzyme 38
    ubiquitin specific protease 38
    ubiquitin thioesterase 38
    ubiquitin thiolesterase 38
    ubiquitin-specific-processing protease 38
    NP_081830.2
    XP_006531513.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027554.2NP_081830.2  ubiquitin carboxyl-terminal hydrolase 38

      See identical proteins and their annotated locations for NP_081830.2

      Status: PROVISIONAL

      Source sequence(s)
      BC054404
      Consensus CDS
      CCDS22444.1
      UniProtKB/Swiss-Prot
      Q8BW70
      Related
      ENSMUSP00000039943.7, ENSMUST00000042724.8
      Conserved Domains (2) summary
      cd02664
      Location:446947
      Peptidase_C19H; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      pfam00443
      Location:445946
      UCH; Ubiquitin carboxyl-terminal hydrolase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      81707353..81741631 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006531450.5XP_006531513.1  ubiquitin carboxyl-terminal hydrolase 38 isoform X1

      Conserved Domains (1) summary
      cd02664
      Location:112613
      Peptidase_C19H; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...

    RNA

    1. XR_004934893.1 RNA Sequence

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