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    Pcf11 PCF11 cleavage and polyadenylation factor subunit [ Mus musculus (house mouse) ]

    Gene ID: 74737, updated on 31-Jan-2019

    Summary

    Official Symbol
    Pcf11provided by MGI
    Official Full Name
    PCF11 cleavage and polyadenylation factor subunitprovided by MGI
    Primary source
    MGI:MGI:1919579
    See related
    Ensembl:ENSMUSG00000041328
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C77803; 2500001H09Rik; 5730417B17Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 8.7), CNS E11.5 (RPKM 7.9) and 28 other tissues See more
    Orthologs

    Genomic context

    See Pcf11 in Genome Data Viewer
    Location:
    7; 7 E1
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 7 NC_000073.6 (92643710..92670051, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (99792222..99818422, complement)

    Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 90B Neighboring gene ankyrin repeat domain 42 Neighboring gene predicted gene, 26944 Neighboring gene predicted gene 2551 Neighboring gene RIKEN cDNA 4632427E13 gene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Clone Names

    • KIAA0824

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    RNA polymerase II complex binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    mRNA polyadenylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    termination of RNA polymerase II transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    pre-mRNA cleavage complex 2 protein Pcf11
    Names
    cleavage and polyadenylation factor subunit homolog

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029078.3NP_083354.3  pre-mRNA cleavage complex 2 protein Pcf11

      See identical proteins and their annotated locations for NP_083354.3

      Status: VALIDATED

      Source sequence(s)
      AK173035, BC030492, CJ046746
      Consensus CDS
      CCDS52311.1
      UniProtKB/TrEMBL
      G3X9Z4, Q69ZY3, Q8K0S1
      Related
      ENSMUSP00000113717.1, ENSMUST00000119954.8
      Conserved Domains (1) summary
      cd03562
      Location:19130
      CID; CID (CTD-Interacting Domain) domain family; CID is present in several RNA-processing factors such as Pcf11 and Nrd1. Pcf11 is a conserved and essential subunit of the yeast cleavage factor IA, which is required for polyadenylation-dependent 3'-RNA ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000073.6 Reference GRCm38.p4 C57BL/6J

      Range
      92643710..92670051 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006508272.3XP_006508335.1  pre-mRNA cleavage complex 2 protein Pcf11 isoform X1

      Related
      ENSMUSP00000115278.1, ENSMUST00000151177.1
      Conserved Domains (1) summary
      cd03562
      Location:19130
      CID; CID (CTD-Interacting Domain) domain family; CID is present in several RNA-processing factors such as Pcf11 and Nrd1. Pcf11 is a conserved and essential subunit of the yeast cleavage factor IA, which is required for polyadenylation-dependent 3'-RNA ...
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