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    Scpep1 serine carboxypeptidase 1 [ Mus musculus (house mouse) ]

    Gene ID: 74617, updated on 22-Sep-2018

    Summary

    Official Symbol
    Scpep1provided by MGI
    Official Full Name
    serine carboxypeptidase 1provided by MGI
    Primary source
    MGI:MGI:1921867
    See related
    Ensembl:ENSMUSG00000000278 Vega:OTTMUSG00000001271
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Risc; AI957256; 2410018F01Rik; 4833411K15Rik
    Expression
    Broad expression in placenta adult (RPKM 73.9), bladder adult (RPKM 35.1) and 25 other tissues See more
    Orthologs

    Genomic context

    See Scpep1 in Genome Data Viewer
    Location:
    11; 11 C
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (88924020..88955442, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (88785334..88816756, complement)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA C030037D09 gene Neighboring gene RIKEN cDNA 4930556N13 gene Neighboring gene A kinase (PRKA) anchor protein 1 Neighboring gene serine carboxypeptidase 1, opposite strand Neighboring gene transcription elongation factor B (SIII), polypeptide 2 pseudogene Neighboring gene elongin B-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    carboxypeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    peptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    serine-type carboxypeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    serine-type carboxypeptidase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    negative regulation of blood pressure IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    positive regulation of blood vessel diameter IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    proteolysis involved in cellular protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    retinoid-inducible serine carboxypeptidase
    Names
    retinoid-inducible serine caroboxypeptidase
    retinoid-inducible serine caroboxypetidase
    serine caroboxypeptidase 1
    NP_083299.3

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029023.3NP_083299.3  retinoid-inducible serine carboxypeptidase precursor

      See identical proteins and their annotated locations for NP_083299.3

      Status: VALIDATED

      Source sequence(s)
      AK014680, BX518946
      Consensus CDS
      CCDS25230.1
      UniProtKB/Swiss-Prot
      Q920A5
      Related
      ENSMUSP00000000287.8, OTTMUSP00000001247, ENSMUST00000000287.8, OTTMUST00000002531
      Conserved Domains (1) summary
      pfam00450
      Location:34451
      Peptidase_S10; Serine carboxypeptidase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      88924020..88955442 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCm38.p4 NOD/ShiLtJ

    Genomic

    1. NT_187003.1 Reference GRCm38.p4 NOD/ShiLtJ

      Range
      2058275..2089098 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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