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    Gzf1 GDNF-inducible zinc finger protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 74533, updated on 23-Jun-2021

    Summary

    Official Symbol
    Gzf1provided by MGI
    Official Full Name
    GDNF-inducible zinc finger protein 1provided by MGI
    Primary source
    MGI:MGI:1921783
    See related
    Ensembl:ENSMUSG00000027439
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Zfp33; mGZF1; Zfp336; 8430437G08Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 7.1), placenta adult (RPKM 6.0) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Gzf1 in Genome Data Viewer
    Location:
    2; 2 G3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (148521305..148534869)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (148679384..148692949)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (148506856..148518685)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 25866 Neighboring gene NTF2-related export protein 1 Neighboring gene predicted gene, 46771 Neighboring gene uncharacterized LOC108168731 Neighboring gene N-ethylmaleimide sensitive fusion protein attachment protein beta Neighboring gene predicted gene, 54122

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    GDNF-inducible zinc finger protein 1
    Names
    zinc finger protein 336

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001355689.1NP_001342618.1  GDNF-inducible zinc finger protein 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AL928638
      Consensus CDS
      CCDS16841.1
      Conserved Domains (5) summary
      COG5048
      Location:410538
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:519539
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:317337
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18211
      Location:6133
      BTB_POZ_ZBTB23_GZF1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in glial cell line-derived neurotrophic factor-inducible zinc finger protein 1 (GZF1)
      pfam13465
      Location:531556
      zf-H2C2_2; Zinc-finger double domain
    2. NM_028986.3NP_083262.1  GDNF-inducible zinc finger protein 1

      See identical proteins and their annotated locations for NP_083262.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AK052820, BC096015, BY123697
      Consensus CDS
      CCDS16841.1
      UniProtKB/Swiss-Prot
      Q4VBD9
      Related
      ENSMUSP00000028928.8, ENSMUST00000028928.8
      Conserved Domains (5) summary
      COG5048
      Location:410538
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:519539
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:317337
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18211
      Location:6133
      BTB_POZ_ZBTB23_GZF1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in glial cell line-derived neurotrophic factor-inducible zinc finger protein 1 (GZF1)
      pfam13465
      Location:531556
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      148521305..148534869
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036162645.1XP_036018538.1  GDNF-inducible zinc finger protein 1 isoform X1

      Conserved Domains (5) summary
      COG5048
      Location:410538
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:519539
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:317337
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18211
      Location:6133
      BTB_POZ_ZBTB23_GZF1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in glial cell line-derived neurotrophic factor-inducible zinc finger protein 1 (GZF1)
      pfam13465
      Location:531556
      zf-H2C2_2; Zinc-finger double domain
    2. XM_006500305.5XP_006500368.1  GDNF-inducible zinc finger protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006500368.1

      UniProtKB/Swiss-Prot
      Q4VBD9
      Conserved Domains (5) summary
      COG5048
      Location:410538
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:519539
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:317337
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18211
      Location:6133
      BTB_POZ_ZBTB23_GZF1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in glial cell line-derived neurotrophic factor-inducible zinc finger protein 1 (GZF1)
      pfam13465
      Location:531556
      zf-H2C2_2; Zinc-finger double domain

    RNA

    1. XR_004940758.1 RNA Sequence

    2. XR_003953729.2 RNA Sequence

    3. XR_003953730.2 RNA Sequence

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