Format

Send to:

Choose Destination
    • Showing Current items.

    Morc2a microrchidia 2A [ Mus musculus (house mouse) ]

    Gene ID: 74522, updated on 19-Mar-2019

    Summary

    Official Symbol
    Morc2aprovided by MGI
    Official Full Name
    microrchidia 2Aprovided by MGI
    Primary source
    MGI:MGI:1921772
    See related
    Ensembl:ENSMUSG00000034543
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Zcwcc1; 8430403M08Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 13.7), CNS E14 (RPKM 13.3) and 28 other tissues See more
    Orthologs

    Genomic context

    See Morc2a in Genome Data Viewer
    Location:
    11; 11 A1
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (3649257..3690477)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (3549497..3590375)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene interferon-induced transmembrane protein 3-like Neighboring gene taurine upregulated gene 1 Neighboring gene nucleolar and spindle associated protein 1 pseudogene Neighboring gene oxysterol binding protein 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding ISO
    Inferred from Sequence Orthology
    more info
     
    ATPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    chromatin binding ISO
    Inferred from Sequence Orthology
    more info
     
    histone binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    magnesium ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    zinc ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    heterochromatin ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear matrix ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ATPase MORC2A; MORC family CW-type zinc finger protein 2A
    Names
    zinc finger CW-type coiled-coil domain protein 1
    zinc finger, CW-type with coiled-coil domain 1
    NP_001152760.1
    NP_937805.1
    XP_006514934.1
    XP_011242077.1
    XP_011242078.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001159288.2NP_001152760.1  ATPase MORC2A isoform 1

      See identical proteins and their annotated locations for NP_001152760.1

      Status: VALIDATED

      Source sequence(s)
      AK173042, AL691413
      Consensus CDS
      CCDS48741.1
      UniProtKB/Swiss-Prot
      Q69ZX6
      Related
      ENSMUSP00000091087.2, ENSMUST00000093389.8
      Conserved Domains (3) summary
      pfam07496
      Location:495542
      zf-CW; CW-type Zinc Finger
      pfam13589
      Location:29169
      HATPase_c_3; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
      cl26464
      Location:624741
      Atrophin-1; Atrophin-1 family
    2. NM_001363202.1NP_001350131.1  ATPase MORC2A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL691413
      Conserved Domains (3) summary
      pfam07496
      Location:495542
      zf-CW; CW-type Zinc Finger
      pfam13589
      Location:29169
      HATPase_c_3; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
      cl26464
      Location:624741
      Atrophin-1; Atrophin-1 family
    3. NM_198162.2NP_937805.1  ATPase MORC2A isoform 2

      See identical proteins and their annotated locations for NP_937805.1

      Status: VALIDATED

      Source sequence(s)
      AL691413, BC059243
      UniProtKB/TrEMBL
      Q6PCN6
      Conserved Domains (3) summary
      pfam05843
      Location:558644
      Suf; Suppressor of forked protein (Suf)
      pfam07496
      Location:433480
      zf-CW; CW-type Zinc Finger
      cl00075
      Location:1107
      HATPase_c; Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      3649257..3690477
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011243775.2XP_011242077.1  MORC family CW-type zinc finger protein 2A isoform X1

      See identical proteins and their annotated locations for XP_011242077.1

      Conserved Domains (3) summary
      pfam05843
      Location:620706
      Suf; Suppressor of forked protein (Suf)
      pfam07496
      Location:495542
      zf-CW; CW-type Zinc Finger
      pfam13589
      Location:29169
      HATPase_c_3; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
    2. XM_011243776.2XP_011242078.1  MORC family CW-type zinc finger protein 2A isoform X2

      UniProtKB/Swiss-Prot
      Q69ZX6
      Related
      ENSMUSP00000094176.3, ENSMUST00000096441.3
      Conserved Domains (3) summary
      pfam07496
      Location:495542
      zf-CW; CW-type Zinc Finger
      pfam13589
      Location:29169
      HATPase_c_3; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
      cl26464
      Location:624741
      Atrophin-1; Atrophin-1 family
    3. XM_006514871.3XP_006514934.1  MORC family CW-type zinc finger protein 2A isoform X1

      See identical proteins and their annotated locations for XP_006514934.1

      Conserved Domains (3) summary
      pfam05843
      Location:620706
      Suf; Suppressor of forked protein (Suf)
      pfam07496
      Location:495542
      zf-CW; CW-type Zinc Finger
      pfam13589
      Location:29169
      HATPase_c_3; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
    Support Center