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    Gle1 GLE1 RNA export mediator (yeast) [ Mus musculus (house mouse) ]

    Gene ID: 74412, updated on 23-Jun-2021

    Summary

    Official Symbol
    Gle1provided by MGI
    Official Full Name
    GLE1 RNA export mediator (yeast)provided by MGI
    Primary source
    MGI:MGI:1921662
    See related
    Ensembl:ENSMUSG00000019715
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gle1l; AA553313; 4933405K21Rik
    Expression
    Ubiquitous expression in cerebellum adult (RPKM 15.0), CNS E18 (RPKM 14.4) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Gle1 in Genome Data Viewer
    Location:
    2; 2 B
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (29825421..29849444)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (29935409..29959432)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (29790929..29814952)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene cerebral endothelial cell adhesion molecule Neighboring gene RIKEN cDNA 2600006K01 gene Neighboring gene outer dense fiber of sperm tails 2 Neighboring gene spectrin alpha, non-erythrocytic 1 Neighboring gene microRNA 6997 Neighboring gene dynein 2 intermediate chain 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables inositol hexakisphosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables phospholipid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables translation initiation factor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in mRNA export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within mRNA transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in poly(A)+ mRNA export from nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of translational initiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in regulation of translational termination IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in centriole ISO
    Inferred from Sequence Orthology
    more info
     
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in ciliary basal body ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear envelope ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
     
    part_of nuclear pore IEA
    Inferred from Electronic Annotation
    more info
     
    part_of nuclear pore cytoplasmic filaments IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    nucleoporin GLE1
    Names
    GLE1-like protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028923.3NP_083199.1  nucleoporin GLE1

      See identical proteins and their annotated locations for NP_083199.1

      Status: VALIDATED

      Source sequence(s)
      AK145748, AL928926, BY673167
      Consensus CDS
      CCDS15862.1
      UniProtKB/Swiss-Prot
      Q8R322
      Related
      ENSMUSP00000019859.9, ENSMUST00000019859.9
      Conserved Domains (2) summary
      pfam07817
      Location:410648
      GLE1; GLE1-like protein
      cl23765
      Location:169288
      iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      29825421..29849444
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036162642.1XP_036018535.1  nucleoporin GLE1 isoform X1

      Conserved Domains (1) summary
      pfam07817
      Location:92327
      GLE1; GLE1-like protein
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