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    Rmi1 RecQ mediated genome instability 1 [ Mus musculus (house mouse) ]

    Gene ID: 74386, updated on 23-Jun-2021

    Summary

    Official Symbol
    Rmi1provided by MGI
    Official Full Name
    RecQ mediated genome instability 1provided by MGI
    Primary source
    MGI:MGI:1921636
    See related
    Ensembl:ENSMUSG00000035367
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C79893; 4932432N11Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 11.8), CNS E14 (RPKM 10.3) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Rmi1 in Genome Data Viewer
    Location:
    13; 13 B1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (58550062..58558963)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (58402248..58411149)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (58503609..58512510)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 2210016F16 gene Neighboring gene heterogeneous nuclear ribonucleoprotein K Neighboring gene microRNA 7-1 Neighboring gene predicted gene, 33875 Neighboring gene predicted gene, 47918 Neighboring gene predicted gene, 40966

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of RecQ family helicase-topoisomerase III complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in nuclear body IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    recQ-mediated genome instability protein 1
    Names
    RMI1, RecQ mediated genome instability 1, homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001168248.1NP_001161720.1  recQ-mediated genome instability protein 1

      See identical proteins and their annotated locations for NP_001161720.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AC154437
      Consensus CDS
      CCDS26571.1
      UniProtKB/Swiss-Prot
      Q9D4G9
      Related
      ENSMUSP00000153621.2, ENSMUST00000225815.2
      Conserved Domains (2) summary
      pfam08585
      Location:14204
      RMI1_N; RecQ mediated genome instability protein
      pfam16099
      Location:480610
      RMI1_C; Recq-mediated genome instability protein 1, C-terminal OB-fold
    2. NM_028904.3NP_083180.3  recQ-mediated genome instability protein 1

      See identical proteins and their annotated locations for NP_083180.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AC154437, AK016542
      Consensus CDS
      CCDS26571.1
      UniProtKB/Swiss-Prot
      Q9D4G9
      Related
      ENSMUSP00000041035.9, ENSMUST00000042450.10
      Conserved Domains (2) summary
      pfam08585
      Location:14204
      RMI1_N; RecQ mediated genome instability protein
      pfam16099
      Location:480610
      RMI1_C; Recq-mediated genome instability protein 1, C-terminal OB-fold

    RNA

    1. NR_031761.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) has an alternate 5' exon, compared to variant 1. This variant is represented as non-coding due to the presence of an upstream ORF that is predicted to interfere with translation of the longest ORF; translation of the upstream ORF renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC154437, AK079457

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      58550062..58558963
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006517420.5XP_006517483.1  recQ-mediated genome instability protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006517483.1

      UniProtKB/Swiss-Prot
      Q9D4G9
      Related
      ENSMUSP00000153050.2, ENSMUST00000224479.2
      Conserved Domains (2) summary
      pfam08585
      Location:14204
      RMI1_N; RecQ mediated genome instability protein
      pfam16099
      Location:480610
      RMI1_C; Recq-mediated genome instability protein 1, C-terminal OB-fold
    2. XM_036158198.1XP_036014091.1  recQ-mediated genome instability protein 1 isoform X1

      Conserved Domains (2) summary
      pfam08585
      Location:14204
      RMI1_N; RecQ mediated genome instability protein
      pfam16099
      Location:480610
      RMI1_C; Recq-mediated genome instability protein 1, C-terminal OB-fold
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