Format

Send to:

Choose Destination
    • Showing Current items.

    Lonrf3 LON peptidase N-terminal domain and ring finger 3 [ Mus musculus (house mouse) ]

    Gene ID: 74365, updated on 12-Aug-2018

    Summary

    Official Symbol
    Lonrf3provided by MGI
    Official Full Name
    LON peptidase N-terminal domain and ring finger 3provided by MGI
    Primary source
    MGI:MGI:1921615
    See related
    Ensembl:ENSMUSG00000016239 Vega:OTTMUSG00000017249
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rnf127; AU023707; 4932412G04Rik; 5730439E01Rik; A830039N02Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 2.7), placenta adult (RPKM 2.6) and 26 other tissues See more
    Orthologs

    Genomic context

    See Lonrf3 in Genome Data Viewer
    Location:
    X; X A3.3
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) X NC_000086.7 (36328358..36366857)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (33868404..33906851)

    Chromosome X - NC_000086.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 42406 Neighboring gene zinc finger, CCHC domain containing 12 Neighboring gene predicted gene 6023 Neighboring gene predicted gene, 33383 Neighboring gene predicted gene 6268

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    LON peptidase N-terminal domain and RING finger protein 3
    Names
    ring finger protein 127

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028894.1NP_083170.1  LON peptidase N-terminal domain and RING finger protein 3

      See identical proteins and their annotated locations for NP_083170.1

      Status: VALIDATED

      Source sequence(s)
      AK016522, AL450395, BC058671, BY740851
      Consensus CDS
      CCDS30059.1
      UniProtKB/Swiss-Prot
      Q9D4H7
      Related
      ENSMUSP00000016383.3, OTTMUSP00000018759, ENSMUST00000016383.9, OTTMUST00000041737
      Conserved Domains (7) summary
      COG5152
      Location:340498
      COG5152; Uncharacterized conserved protein, contains RING and CCCH-type Zn-fingers [General function prediction only]
      cd00162
      Location:460499
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cl19481
      Location:560746
      LON; Found in ATP-dependent protease La (LON)
      sd00006
      Location:244272
      TPR; TPR repeat [structural motif]
      pfam02190
      Location:549750
      LON_substr_bdg; ATP-dependent protease La (LON) substrate-binding domain
      pfam13414
      Location:243309
      TPR_11; TPR repeat
      pfam14634
      Location:158197
      zf-RING_5; zinc-RING finger domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000086.7 Reference GRCm38.p4 C57BL/6J

      Range
      36328358..36366857
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006541404.1XP_006541467.1  LON peptidase N-terminal domain and RING finger protein 3 isoform X1

      Conserved Domains (6) summary
      cd00162
      Location:512551
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cl19481
      Location:612798
      LON; Found in ATP-dependent protease La (LON)
      sd00006
      Location:244272
      TPR; TPR repeat [structural motif]
      pfam02190
      Location:601802
      LON_substr_bdg; ATP-dependent protease La (LON) substrate-binding domain
      pfam13414
      Location:243309
      TPR_11; TPR repeat
      pfam14634
      Location:158197
      zf-RING_5; zinc-RING finger domain
    Support Center