Format

Send to:

Choose Destination
    • Showing Current items.

    Smu1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) [ Mus musculus (house mouse) ]

    Gene ID: 74255, updated on 9-Sep-2018

    Summary

    Official Symbol
    Smu1provided by MGI
    Official Full Name
    smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)provided by MGI
    Primary source
    MGI:MGI:1915546
    See related
    Ensembl:ENSMUSG00000028409 Vega:OTTMUSG00000006607
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Bwd; AB044414; AI845086; AW556129; 2600001O03Rik; 2610203K23Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 30.9), placenta adult (RPKM 27.4) and 27 other tissues See more
    Orthologs

    Genomic context

    See Smu1 in Genome Data Viewer
    Location:
    4; 4 A5
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (40735649..40757885, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (40682682..40704918, complement)

    Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene aprataxin Neighboring gene predicted gene 6297 Neighboring gene DnaJ heat shock protein family (Hsp40) member A1 Neighboring gene microRNA 207 Neighboring gene predicted gene, 34213 Neighboring gene presenilin enhancer 2 homolog pseudogene Neighboring gene UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 Neighboring gene microRNA 5123

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    RNA splicing IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    mRNA splicing, via spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    U2-type precatalytic spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    WD40 repeat-containing protein SMU1
    Names
    smu-1 suppressor of mec-8 and unc-52 protein homolog

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_021535.4NP_067510.3  WD40 repeat-containing protein SMU1

      See identical proteins and their annotated locations for NP_067510.3

      Status: VALIDATED

      Source sequence(s)
      AK145982, AK163758, AK168813, BY036103
      Consensus CDS
      CCDS18050.1
      UniProtKB/Swiss-Prot
      Q3UKJ7
      Related
      ENSMUSP00000030117.4, OTTMUSP00000006965, ENSMUST00000030117.4, OTTMUST00000015068
      Conserved Domains (5) summary
      smart00667
      Location:538
      LisH; Lissencephaly type-1-like homology motif
      smart00668
      Location:4090
      CTLH; C-terminal to LisH motif
      cd00200
      Location:205512
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:219262
      7WD40; WD40 repeat [structural motif]
      cl28181
      Location:102218
      AAA; ATPases associated with a variety of cellular activities

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

      Range
      40735649..40757885 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center