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    Gale galactose-4-epimerase, UDP [ Mus musculus (house mouse) ]

    Gene ID: 74246, updated on 27-Jan-2018

    Summary

    Official Symbol
    Galeprovided by MGI
    Official Full Name
    galactose-4-epimerase, UDPprovided by MGI
    Primary source
    MGI:MGI:1921496
    See related
    Ensembl:ENSMUSG00000028671 Vega:OTTMUSG00000009851
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI323962; 2310002A12Rik
    Expression
    Broad expression in colon adult (RPKM 100.7), large intestine adult (RPKM 78.5) and 22 other tissues See more
    Orthologs

    Genomic context

    See Gale in Genome Data Viewer
    Location:
    4; 4 D3
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (135963681..135968178)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (135521080..135524093)

    Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene fucosidase, alpha-L- 1, tissue Neighboring gene 3-hydroxy-3-methylglutaryl-Coenzyme A lyase Neighboring gene lysophospholipase 2 Neighboring gene PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    UDP-N-acetylglucosamine 4-epimerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    UDP-glucose 4-epimerase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    UDP-glucose 4-epimerase activity ISO
    Inferred from Sequence Orthology
    more info
     
    identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    racemase and epimerase activity, acting on carbohydrates and derivatives IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    galactose catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    galactose catabolic process via UDP-galactose IC
    Inferred by Curator
    more info
    PubMed 
    galactose metabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    glycolytic process from galactose IC
    Inferred by Curator
    more info
    PubMed 

    General protein information

    Preferred Names
    UDP-glucose 4-epimerase
    Names
    UDP-GalNAc 4-epimerase
    UDP-GlcNAc 4-epimerase
    UDP-N-acetylglucosamine 4-epimerase
    UDP-galactosamine 4-epimerase
    UDP-galactose 4-epimerase
    galactowaldenase
    XP_006539280.1
    XP_006539281.1
    XP_006539282.1
    XP_006539283.1
    XP_017175904.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001356493.1NP_001343422.1  UDP-glucose 4-epimerase

      Status: VALIDATED

      Source sequence(s)
      AI847878, AL672076, AW544394, BB854114, BG077710, CO429161
      Consensus CDS
      CCDS18796.1
      Conserved Domains (1) summary
      cd05247
      Location:3337
      UDP_G4E_1_SDR_e; UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

      Range
      135963681..135968178
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006539217.1XP_006539280.1  UDP-glucose 4-epimerase isoform X1

      UniProtKB/Swiss-Prot
      Q8R059
      Related
      ENSMUSP00000099600.3, OTTMUSP00000010415, ENSMUST00000102541.9, OTTMUST00000022836
      Conserved Domains (1) summary
      cd05247
      Location:3337
      UDP_G4E_1_SDR_e; UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs
    2. XM_006539218.3XP_006539281.1  UDP-glucose 4-epimerase isoform X1

      See identical proteins and their annotated locations for XP_006539281.1

      UniProtKB/Swiss-Prot
      Q8R059
      Conserved Domains (1) summary
      cd05247
      Location:3337
      UDP_G4E_1_SDR_e; UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs
    3. XM_006539219.3XP_006539282.1  UDP-glucose 4-epimerase isoform X1

      See identical proteins and their annotated locations for XP_006539282.1

      UniProtKB/Swiss-Prot
      Q8R059
      Conserved Domains (1) summary
      cd05247
      Location:3337
      UDP_G4E_1_SDR_e; UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs
    4. XM_017320415.1XP_017175904.1  UDP-glucose 4-epimerase isoform X3

    5. XM_006539220.2XP_006539283.1  UDP-glucose 4-epimerase isoform X2

      Conserved Domains (1) summary
      cd05247
      Location:1220
      UDP_G4E_1_SDR_e; UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_178389.3: Suppressed sequence

      Description
      NM_178389.3: This RefSeq was removed because currently there is insufficient support for the transcript.
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