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    Gtf2e1 general transcription factor II E, polypeptide 1 (alpha subunit) [ Mus musculus (house mouse) ]

    Gene ID: 74197, updated on 31-Jan-2019

    Summary

    Official Symbol
    Gtf2e1provided by MGI
    Official Full Name
    general transcription factor II E, polypeptide 1 (alpha subunit)provided by MGI
    Primary source
    MGI:MGI:1921447
    See related
    Ensembl:ENSMUSG00000022828
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    FE; 56kDa; TFIIE-A; AI303800; 2610024P03Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 12.8), CNS E14 (RPKM 8.7) and 25 other tissues See more
    Orthologs

    Genomic context

    See Gtf2e1 in Genome Data Viewer
    Location:
    16; 16 B3
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 16 NC_000082.6 (37509795..37539773, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (37509882..37539855, complement)

    Chromosome 16 - NC_000082.6Genomic Context describing neighboring genes Neighboring gene polymerase (DNA directed), theta Neighboring gene syntaxin binding protein 5-like Neighboring gene LIM and senescent cell antigen like domains 2 pseudogene Neighboring gene RAB, member RAS oncogene family-like 3 Neighboring gene predicted gene, 46559 Neighboring gene homogentisate 1, 2-dioxygenase

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    RNA polymerase II complex binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    RNA polymerase II general transcription initiation factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    TFIIH-class transcription factor complex binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    transcription initiation from RNA polymerase II promoter IEA
    Inferred from Electronic Annotation
    more info
     
    transcriptional open complex formation at RNA polymerase II promoter IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    transcription factor TFIID complex ISO
    Inferred from Sequence Orthology
    more info
     
    transcription factor TFIIE complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transcriptional preinitiation complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    general transcription factor IIE subunit 1
    Names
    TFIIE-alpha
    general transcription factor II E, polypeptide 1 (alpha subunit, 56kDa)
    general transcription factor IIE 56 kDa subunit
    general transcription factor IIE, polypeptide 1 (alpha subunit, 56kDa)
    transcription initiation factor IIE subunit alpha

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001355727.1NP_001342656.1  general transcription factor IIE subunit 1

      Status: VALIDATED

      Source sequence(s)
      AC154762
      Conserved Domains (2) summary
      smart00531
      Location:28175
      TFIIE; Transcription initiation factor IIE
      pfam11521
      Location:395440
      TFIIE-A_C; C-terminal general transcription factor TFIIE alpha
    2. NM_028812.4NP_083088.1  general transcription factor IIE subunit 1

      See identical proteins and their annotated locations for NP_083088.1

      Status: VALIDATED

      Source sequence(s)
      AC154762
      Consensus CDS
      CCDS28160.1
      UniProtKB/Swiss-Prot
      Q9D0D5
      Related
      ENSMUSP00000023525.8, ENSMUST00000023525.8
      Conserved Domains (2) summary
      smart00531
      Location:28175
      TFIIE; Transcription initiation factor IIE
      pfam11521
      Location:395440
      TFIIE-A_C; C-terminal general transcription factor TFIIE alpha

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000082.6 Reference GRCm38.p4 C57BL/6J

      Range
      37509795..37539773 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006522659.3XP_006522722.1  general transcription factor IIE subunit 1 isoform X1

      UniProtKB/Swiss-Prot
      Q9D0D5
      Conserved Domains (2) summary
      smart00531
      Location:28175
      TFIIE; Transcription initiation factor IIE
      pfam11521
      Location:395440
      TFIIE-A_C; C-terminal general transcription factor TFIIE alpha
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