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    Acbd5 acyl-Coenzyme A binding domain containing 5 [ Mus musculus (house mouse) ]

    Gene ID: 74159, updated on 31-Jan-2019

    Summary

    Official Symbol
    Acbd5provided by MGI
    Official Full Name
    acyl-Coenzyme A binding domain containing 5provided by MGI
    Primary source
    MGI:MGI:1921409
    See related
    Ensembl:ENSMUSG00000026781
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1300014E15Rik
    Expression
    Ubiquitous expression in cerebellum adult (RPKM 8.7), frontal lobe adult (RPKM 8.4) and 28 other tissues See more
    Orthologs

    Genomic context

    See Acbd5 in Genome Data Viewer
    Location:
    2; 2 A3
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (23067689..23114513)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (22923721..22970033)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene prenyl (solanesyl) diphosphate synthase, subunit 1 Neighboring gene ribosomal protein L17 pseudogene Neighboring gene abl-interactor 1 Neighboring gene microtubule associated serine/threonine kinase-like Neighboring gene YME1-like 1 (S. cerevisiae) Neighboring gene nucleophosmin 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Clone Names

    • MGC90942

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    fatty-acyl-CoA binding IEA
    Inferred from Electronic Annotation
    more info
     
    lipid binding IEA
    Inferred from Electronic Annotation
    more info
     
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    autophagy IEA
    Inferred from Electronic Annotation
    more info
     
    autophagy of peroxisome ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    peroxisome ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    acyl-CoA-binding domain-containing protein 5

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001102436.1NP_001095906.1  acyl-CoA-binding domain-containing protein 5 isoform d

      See identical proteins and their annotated locations for NP_001095906.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR and coding sequence, lacks an alternate in-frame exon, and uses an alternate in-frame splice junction compared to variant 5. The resulting isoform (c) is shorter at the N-terminus and lacks two alternate internal segments compared to isoform e.
      Source sequence(s)
      AK050450, BC090641, BY070285
      Consensus CDS
      CCDS50516.1
      UniProtKB/Swiss-Prot
      Q5XG73
      UniProtKB/TrEMBL
      Q5CZX6
      Related
      ENSMUSP00000154023.1, ENSMUST00000227809.1
      Conserved Domains (1) summary
      cd00435
      Location:996
      ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...
    2. NM_001102437.1NP_001095907.1  acyl-CoA-binding domain-containing protein 5 isoform a precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) lacks an alternate in-frame exon compared to variant 5. The resulting isoform (a) has the same N- and C-termini but is shorter compared to isoform e.
      Source sequence(s)
      AK005001, AK147839, BC090641, BY126800
      Consensus CDS
      CCDS57156.1
      UniProtKB/Swiss-Prot
      Q5XG73
      UniProtKB/TrEMBL
      E9QNH7, Q5CZX6
      Related
      ENSMUSP00000110175.2, ENSMUST00000114529.9
      Conserved Domains (1) summary
      cd00435
      Location:45132
      ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...
    3. NM_001102438.1NP_001095908.1  acyl-CoA-binding domain-containing protein 5 isoform b precursor

      See identical proteins and their annotated locations for NP_001095908.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon and uses an alternate in-frame splice junction compared to variant 5. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform e.
      Source sequence(s)
      AK050450, AK147839, BC090641, BY126800
      Consensus CDS
      CCDS50514.1
      UniProtKB/Swiss-Prot
      Q5XG73
      UniProtKB/TrEMBL
      Q5CZX6
      Related
      ENSMUSP00000110172.1, ENSMUST00000114526.8
      Conserved Domains (1) summary
      cd00435
      Location:45132
      ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...
    4. NM_001355637.1NP_001342566.1  acyl-CoA-binding domain-containing protein 5 isoform e precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) represents the longest transcript and encodes the longest isoform (e).
      Source sequence(s)
      AL845257
      Conserved Domains (1) summary
      cd00435
      Location:45132
      ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...
    5. NM_001355638.1NP_001342567.1  acyl-CoA-binding domain-containing protein 5 isoform f precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) uses an alternate in-frame splice junction compared to variant 1. The resulting isoform (f) has the same N- and C-termini but is 1 aa shorter compared to isoform e.
      Source sequence(s)
      AL845257
      Conserved Domains (1) summary
      cd00435
      Location:45132
      ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...
    6. NM_001355639.1NP_001342568.1  acyl-CoA-binding domain-containing protein 5 isoform g

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) differs in the 5' UTR and coding sequence and uses an alternate in-frame splice junction compared to variant 5. The resulting isoform (g) is shorter at the N-terminus and lacks an internal single aa compared to isoform e.
      Source sequence(s)
      AL845257
      Conserved Domains (1) summary
      cd00435
      Location:996
      ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...
    7. NM_001355641.1NP_001342570.1  acyl-CoA-binding domain-containing protein 5 isoform h

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8) lacks an alternate exon in the 5' end compared to variant 5. The resulting isoform (h) is shorter at the N-terminus compared to isoform e.
      Source sequence(s)
      AL845257
      Conserved Domains (1) summary
      cl00221
      Location:122
      ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...
    8. NM_001355642.1NP_001342571.1  acyl-CoA-binding domain-containing protein 5 isoform i

      Status: VALIDATED

      Description
      Transcript Variant: This variant (9) differs in the 5' UTR and coding sequence and lacks an alternate in-frame exon compared to variant 5. The resulting isoform (i) is shorter at the N-terminus and lacks an alternate segment compared to isoform e.
      Source sequence(s)
      AL845257
      Conserved Domains (1) summary
      cl00221
      Location:122
      ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...
    9. NM_028793.3NP_083069.1  acyl-CoA-binding domain-containing protein 5 isoform c

      See identical proteins and their annotated locations for NP_083069.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence and lacks an alternate in-frame exon compared to variant 5. The resulting isoform (c) is shorter at the N-terminus and lacks an alternate internal segment compared to isoform e.
      Source sequence(s)
      AK050450, BC090641, BY070285
      Consensus CDS
      CCDS50515.1
      UniProtKB/Swiss-Prot
      Q5XG73
      UniProtKB/TrEMBL
      Q5CZX6
      Related
      ENSMUSP00000028121.8, ENSMUST00000028121.14
      Conserved Domains (1) summary
      cd00435
      Location:996
      ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...

    RNA

    1. NR_149742.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (10) differs in the 5' end and has multiple internal differences compared to variant 5. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AL845257

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

      Range
      23067689..23114513
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017319291.1XP_017174780.1  acyl-CoA-binding domain-containing protein 5 isoform X3

      Related
      ENSMUSP00000154518.1, ENSMUST00000227663.1
      Conserved Domains (1) summary
      cd00435
      Location:996
      ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...
    2. XM_006498385.3XP_006498448.1  acyl-CoA-binding domain-containing protein 5 isoform X2

      Related
      ENSMUSP00000117325.2, ENSMUST00000155602.3
      Conserved Domains (1) summary
      cd00435
      Location:996
      ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...
    3. XM_006498386.3XP_006498449.1  acyl-CoA-binding domain-containing protein 5 isoform X4

      Related
      ENSMUSP00000154043.1, ENSMUST00000228050.1
      Conserved Domains (1) summary
      cd00435
      Location:45132
      ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...
    4. XM_006498387.1XP_006498450.1  acyl-CoA-binding domain-containing protein 5 isoform X5

      Conserved Domains (1) summary
      cl00221
      Location:122
      ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...
    5. XM_017319292.1XP_017174781.1  acyl-CoA-binding domain-containing protein 5 isoform X6

      Conserved Domains (1) summary
      cl00221
      Location:122
      ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...
    6. XM_011239202.1XP_011237504.1  acyl-CoA-binding domain-containing protein 5 isoform X1

      Related
      ENSMUSP00000154188.1, ENSMUST00000226571.1
      Conserved Domains (1) summary
      cd00435
      Location:45132
      ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...
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